KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB2
All Species:
8.79
Human Site:
T495
Identified Species:
17.58
UniProt:
Q00722
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00722
NP_004564.2
1185
134024
T495
S
A
P
A
G
E
G
T
V
W
A
G
E
E
G
Chimpanzee
Pan troglodytes
XP_001141721
1185
134063
T495
S
A
P
A
G
E
G
T
V
W
A
G
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001095135
1181
134067
A491
S
S
P
R
S
A
P
A
V
W
A
G
E
E
G
Dog
Lupus familis
XP_544615
1188
134303
T495
N
A
S
V
G
E
G
T
V
W
P
G
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
A3KGF7
1181
134528
G496
V
P
V
E
E
D
T
G
W
T
A
E
D
R
T
Rat
Rattus norvegicus
O89040
1183
134864
A499
E
E
D
T
G
W
T
A
E
D
R
T
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
Y489
S
E
Q
A
S
N
T
Y
S
D
T
S
S
V
F
Chicken
Gallus gallus
Q2VRL0
637
72514
L98
D
T
E
L
T
A
F
L
K
K
E
Q
F
K
T
Frog
Xenopus laevis
Q32NH8
758
87399
G219
F
Q
D
F
S
K
D
G
K
K
L
T
L
L
E
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
R519
G
G
E
K
L
A
E
R
M
A
K
D
H
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
Q548
G
H
A
P
P
L
Q
Q
I
R
Q
S
S
K
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
G39
A
F
V
E
Y
T
E
G
R
S
H
M
T
A
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
91.5
N.A.
85.9
85.9
N.A.
44.7
21.5
23.9
42.5
N.A.
35.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.5
94.9
N.A.
90.7
90.8
N.A.
65.3
33.9
35.4
61.1
N.A.
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
73.3
N.A.
6.6
13.3
N.A.
13.3
0
0
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
80
N.A.
20
13.3
N.A.
13.3
6.6
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
9
25
0
25
0
17
0
9
34
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
17
0
0
9
9
0
0
17
0
9
9
9
9
% D
% Glu:
9
17
17
17
9
25
17
0
9
0
9
9
42
34
25
% E
% Phe:
9
9
0
9
0
0
9
0
0
0
0
0
9
0
9
% F
% Gly:
17
9
0
0
34
0
25
25
0
0
0
34
0
0
34
% G
% His:
0
9
0
0
0
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
17
17
9
0
0
17
0
% K
% Leu:
0
0
0
9
9
9
0
9
0
0
9
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
25
9
9
0
9
0
0
0
9
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
9
9
0
0
9
9
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
9
9
9
9
0
0
9
0
% R
% Ser:
34
9
9
0
25
0
0
0
9
9
0
17
17
0
0
% S
% Thr:
0
9
0
9
9
9
25
25
0
9
9
17
9
0
17
% T
% Val:
9
0
17
9
0
0
0
0
34
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
9
0
0
9
34
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _