KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB2
All Species:
33.94
Human Site:
S575
Identified Species:
67.88
UniProt:
Q00722
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00722
NP_004564.2
1185
134024
S575
N
R
S
Y
V
I
S
S
F
T
E
L
K
A
Y
Chimpanzee
Pan troglodytes
XP_001141721
1185
134063
S575
N
R
S
Y
V
I
S
S
F
T
E
L
K
A
Y
Rhesus Macaque
Macaca mulatta
XP_001095135
1181
134067
S571
N
R
S
Y
V
I
S
S
F
T
E
L
K
A
Y
Dog
Lupus familis
XP_544615
1188
134303
S575
N
R
S
Y
V
I
S
S
F
T
E
L
K
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
A3KGF7
1181
134528
S576
N
R
S
Y
V
V
S
S
F
T
E
L
K
A
Y
Rat
Rattus norvegicus
O89040
1183
134864
S579
N
R
S
Y
L
V
S
S
F
T
E
L
K
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
S569
N
K
S
F
E
M
S
S
F
V
E
T
K
G
L
Chicken
Gallus gallus
Q2VRL0
637
72514
S178
S
H
N
T
Y
L
V
S
D
Q
L
I
G
P
S
Frog
Xenopus laevis
Q32NH8
758
87399
Y299
M
M
Q
P
L
C
H
Y
F
I
S
S
S
H
N
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
S599
K
K
F
F
E
M
S
S
F
V
E
T
K
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
S628
N
R
C
Y
E
M
S
S
F
D
E
K
Q
A
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
S119
Q
D
M
A
S
P
L
S
H
Y
F
I
Y
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
91.5
N.A.
85.9
85.9
N.A.
44.7
21.5
23.9
42.5
N.A.
35.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.5
94.9
N.A.
90.7
90.8
N.A.
65.3
33.9
35.4
61.1
N.A.
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
46.6
6.6
6.6
33.3
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
66.6
33.3
13.3
53.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
59
0
% A
% Cys:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
25
0
0
0
0
0
75
0
0
0
0
% E
% Phe:
0
0
9
17
0
0
0
0
84
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
0
% G
% His:
0
9
0
0
0
0
9
0
9
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
34
0
0
0
9
0
17
0
0
0
% I
% Lys:
9
17
0
0
0
0
0
0
0
0
0
9
67
0
0
% K
% Leu:
0
0
0
0
17
9
9
0
0
0
9
50
0
0
9
% L
% Met:
9
9
9
0
0
25
0
0
0
0
0
0
0
0
9
% M
% Asn:
67
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
0
9
0
0
0
0
0
0
0
9
0
% P
% Gln:
9
0
9
0
0
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
59
0
9
0
75
92
0
0
9
9
9
0
17
% S
% Thr:
0
0
0
9
0
0
0
0
0
50
0
17
0
9
9
% T
% Val:
0
0
0
0
42
17
9
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
59
9
0
0
9
0
9
0
0
9
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _