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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB2
All Species:
5.45
Human Site:
S472
Identified Species:
10.91
UniProt:
Q00722
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00722
NP_004564.2
1185
134024
S472
N
Q
F
S
G
P
T
S
S
S
K
D
T
G
G
Chimpanzee
Pan troglodytes
XP_001141721
1185
134063
S472
N
Q
F
S
G
P
T
S
S
S
K
D
T
G
G
Rhesus Macaque
Macaca mulatta
XP_001095135
1181
134067
S468
K
N
K
K
N
Q
F
S
S
P
T
S
S
S
K
Dog
Lupus familis
XP_544615
1188
134303
A472
N
Q
F
S
G
P
A
A
P
S
K
E
S
G
G
Cat
Felis silvestris
Mouse
Mus musculus
A3KGF7
1181
134528
P473
Q
F
S
G
P
A
S
P
S
K
K
P
G
G
V
Rat
Rattus norvegicus
O89040
1183
134864
K476
G
P
A
S
P
N
K
K
P
D
G
V
S
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
K466
Y
K
I
L
V
K
N
K
K
K
S
H
K
S
S
Chicken
Gallus gallus
Q2VRL0
637
72514
F75
A
I
V
H
R
N
E
F
H
E
I
F
C
A
Y
Frog
Xenopus laevis
Q32NH8
758
87399
V196
T
L
E
G
E
E
F
V
L
F
Y
K
A
L
T
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
N496
D
E
Q
S
S
P
L
N
D
C
P
L
S
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
G525
V
T
R
S
T
A
N
G
D
V
A
T
G
T
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
D16
K
M
G
L
C
C
S
D
K
L
R
M
N
R
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
91.5
N.A.
85.9
85.9
N.A.
44.7
21.5
23.9
42.5
N.A.
35.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.5
94.9
N.A.
90.7
90.8
N.A.
65.3
33.9
35.4
61.1
N.A.
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
66.6
N.A.
20
13.3
N.A.
0
0
0
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
26.6
20
N.A.
6.6
0
0
46.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
17
9
9
0
0
9
0
9
9
0
% A
% Cys:
0
0
0
0
9
9
0
0
0
9
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
17
9
0
17
0
9
0
% D
% Glu:
0
9
9
0
9
9
9
0
0
9
0
9
0
9
0
% E
% Phe:
0
9
25
0
0
0
17
9
0
9
0
9
0
0
0
% F
% Gly:
9
0
9
17
25
0
0
9
0
0
9
0
17
34
59
% G
% His:
0
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
17
9
9
9
0
9
9
17
17
17
34
9
9
0
9
% K
% Leu:
0
9
0
17
0
0
9
0
9
9
0
9
0
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
25
9
0
0
9
17
17
9
0
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
17
34
0
9
17
9
9
9
0
0
0
% P
% Gln:
9
25
9
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
9
0
0
0
0
0
9
0
0
9
0
% R
% Ser:
0
0
9
50
9
0
17
25
34
25
9
9
34
17
9
% S
% Thr:
9
9
0
0
9
0
17
0
0
0
9
9
17
9
9
% T
% Val:
9
0
9
0
9
0
0
9
0
9
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _