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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB2
All Species:
12.42
Human Site:
S1036
Identified Species:
24.85
UniProt:
Q00722
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00722
NP_004564.2
1185
134024
S1036
L
K
A
L
K
E
T
S
E
N
D
T
K
E
M
Chimpanzee
Pan troglodytes
XP_001141721
1185
134063
S1036
L
K
A
L
K
E
T
S
E
N
D
T
K
E
M
Rhesus Macaque
Macaca mulatta
XP_001095135
1181
134067
A1032
L
K
A
L
K
E
T
A
E
I
D
T
K
E
M
Dog
Lupus familis
XP_544615
1188
134303
L1039
L
K
T
L
K
E
T
L
E
T
D
T
K
E
M
Cat
Felis silvestris
Mouse
Mus musculus
A3KGF7
1181
134528
S1032
L
K
T
F
K
E
T
S
E
T
D
T
K
E
M
Rat
Rattus norvegicus
O89040
1183
134864
S1034
L
K
S
F
K
E
T
S
E
T
D
T
K
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
E1059
N
Q
L
K
K
L
K
E
I
C
E
K
E
K
K
Chicken
Gallus gallus
Q2VRL0
637
72514
S526
S
G
H
Q
L
P
P
S
N
L
S
K
S
N
K
Frog
Xenopus laevis
Q32NH8
758
87399
D647
S
K
E
G
S
I
V
D
P
L
V
R
V
E
I
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
K1067
C
Q
A
A
Q
I
K
K
L
K
D
V
C
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
L1159
T
K
Q
L
K
A
S
L
D
K
V
T
G
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
R467
G
W
D
S
G
F
Q
R
T
C
F
N
T
W
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
91.5
N.A.
85.9
85.9
N.A.
44.7
21.5
23.9
42.5
N.A.
35.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.5
94.9
N.A.
90.7
90.8
N.A.
65.3
33.9
35.4
61.1
N.A.
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
80
80
N.A.
6.6
6.6
13.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
80
86.6
N.A.
33.3
6.6
20
33.3
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
9
0
9
0
9
0
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
9
0
59
0
0
9
0
% D
% Glu:
0
0
9
0
0
50
0
9
50
0
9
0
9
67
0
% E
% Phe:
0
0
0
17
0
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
9
0
9
9
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
17
0
0
9
9
0
0
0
0
9
% I
% Lys:
0
67
0
9
67
0
17
9
0
17
0
17
50
9
25
% K
% Leu:
50
0
9
42
9
9
0
17
9
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% M
% Asn:
9
0
0
0
0
0
0
0
9
17
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
9
9
0
9
0
0
0
0
0
0
% P
% Gln:
0
17
9
9
9
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% R
% Ser:
17
0
9
9
9
0
9
42
0
0
9
0
9
0
9
% S
% Thr:
9
0
17
0
0
0
50
0
9
25
0
59
9
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
17
9
9
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _