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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK16
All Species:
27.88
Human Site:
Y398
Identified Species:
51.11
UniProt:
Q00536
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00536
NP_006192.1
496
55716
Y398
S
N
E
E
F
K
T
Y
N
Y
P
K
Y
R
A
Chimpanzee
Pan troglodytes
XP_521035
762
83144
Y664
S
N
E
E
F
K
T
Y
N
Y
P
K
Y
R
A
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
Y387
S
N
E
E
F
K
T
Y
N
Y
P
K
Y
R
A
Dog
Lupus familis
XP_538015
500
56072
Y402
S
N
E
E
F
K
T
Y
N
Y
P
K
Y
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q04735
496
55895
Y398
S
N
E
E
F
R
T
Y
N
Y
P
K
Y
R
A
Rat
Rattus norvegicus
Q63686
496
55746
Y398
S
N
E
E
F
R
T
Y
N
Y
P
K
Y
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521338
549
61821
Y451
S
N
E
E
F
K
T
Y
N
Y
P
K
Y
R
P
Chicken
Gallus gallus
XP_416161
516
58803
L405
L
H
L
I
F
R
L
L
G
T
P
C
Q
E
T
Frog
Xenopus laevis
Q6DJM7
435
49211
T338
H
F
E
P
E
R
F
T
L
Y
G
P
K
N
L
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
L321
N
Y
K
P
E
W
F
L
P
C
K
P
Q
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48609
294
33162
A196
G
C
I
L
A
E
L
A
D
A
G
R
P
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
E196
S
V
G
C
I
F
A
E
M
V
N
Q
K
P
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
E196
S
V
G
C
I
F
A
E
M
I
S
Q
K
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
89.3
97.5
N.A.
97.5
95.5
N.A.
76.1
69.1
45.1
41.9
N.A.
35.4
N.A.
N.A.
N.A.
Protein Similarity:
100
60.8
90.3
98
N.A.
98.9
97.3
N.A.
81
82.9
59.6
55.8
N.A.
43.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
13.3
13.3
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
26.6
20
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
N.A.
45.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
16
8
0
8
0
0
0
0
47
% A
% Cys:
0
8
0
16
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
62
54
16
8
0
16
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
62
16
16
0
0
0
0
0
0
0
16
% F
% Gly:
8
0
16
0
0
0
0
0
8
0
16
0
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
16
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
39
0
0
0
0
8
54
24
0
0
% K
% Leu:
8
0
8
8
0
0
16
16
8
0
0
0
0
8
24
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
8
54
0
0
0
0
0
0
54
0
8
0
0
8
0
% N
% Pro:
0
0
0
16
0
0
0
0
8
0
62
16
8
16
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
16
16
8
0
% Q
% Arg:
0
0
0
0
0
31
0
0
0
0
0
8
0
54
0
% R
% Ser:
70
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
54
8
0
8
0
0
0
0
8
% T
% Val:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
54
0
62
0
0
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _