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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABAT All Species: 13.03
Human Site: S448 Identified Species: 20.48
UniProt: P80404 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P80404 NP_000654.2 500 56439 S448 S F D T P D D S I R N K L I L
Chimpanzee Pan troglodytes XP_510803 500 56467 S448 S F D T P D D S I R N K L I L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851424 497 56301 T445 S F D T P D E T I R N K L I L
Cat Felis silvestris
Mouse Mus musculus P61922 500 56433 A448 S F D T P D E A I R N K L I L
Rat Rattus norvegicus P50554 500 56437 A448 S F D T P D E A I R N K L I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506874 415 46612 H373 C T G K F W A H E Y W G L D D
Chicken Gallus gallus XP_414940 500 56535 A448 S F D T P N D A T R N K L I T
Frog Xenopus laevis NP_001083110 500 56523 E448 S F D T P S D E I R N K I I L
Zebra Danio Brachydanio rerio NP_958906 408 45462 R366 D S I M L K A R N K G V F L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649168 486 54566 K435 A V N C T N T K V R D Q I I G
Honey Bee Apis mellifera XP_392483 499 56324 E448 A F N C A S P E L R D A I I K
Nematode Worm Caenorhab. elegans Q21217 483 53037 S432 A V D F P S G S L R D K F V D
Sea Urchin Strong. purpuratus XP_001203183 503 55243 E452 A I D L S S P E T A A E I V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17649 471 52928 T418 F I A W D L P T G E K R D L L
Red Bread Mold Neurospora crassa Q9P3I3 461 49389 P408 G L Q L S E D P T P V I K A A
Conservation
Percent
Protein Identity: 100 98.8 N.A. 94.1 N.A. 91.1 91.8 N.A. 50.4 87 82.8 58 N.A. 52.4 52 46 50.1
Protein Similarity: 100 99.5 N.A. 97.5 N.A. 96.4 96 N.A. 60.5 94.8 92.5 70.4 N.A. 70.1 70.1 65.8 69.7
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 6.6 73.3 80 0 N.A. 13.3 20 33.3 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 6.6 86.6 86.6 13.3 N.A. 60 53.3 60 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 40.4 24.6
Protein Similarity: N.A. N.A. N.A. N.A. 58.8 40.4
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 27 0 7 0 7 0 14 20 0 7 7 7 0 7 14 % A
% Cys: 7 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 60 0 7 34 34 0 0 0 20 0 7 7 14 % D
% Glu: 0 0 0 0 0 7 20 20 7 7 0 7 0 0 0 % E
% Phe: 7 54 0 7 7 0 0 0 0 0 0 0 14 0 0 % F
% Gly: 7 0 7 0 0 0 7 0 7 0 7 7 0 0 14 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 14 7 0 0 0 0 0 40 0 0 7 27 60 0 % I
% Lys: 0 0 0 7 0 7 0 7 0 7 7 54 7 0 7 % K
% Leu: 0 7 0 14 7 7 0 0 14 0 0 0 47 14 47 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 14 0 0 14 0 0 7 0 47 0 0 0 0 % N
% Pro: 0 0 0 0 54 0 20 7 0 7 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 7 0 67 0 7 0 0 0 % R
% Ser: 47 7 0 0 14 27 0 20 0 0 0 0 0 0 0 % S
% Thr: 0 7 0 47 7 0 7 14 20 0 0 0 0 0 7 % T
% Val: 0 14 0 0 0 0 0 0 7 0 7 7 0 14 0 % V
% Trp: 0 0 0 7 0 7 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _