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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSD11B2
All Species:
18.18
Human Site:
T216
Identified Species:
36.36
UniProt:
P80365
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80365
NP_000187.3
405
44127
T216
S
S
R
G
R
I
V
T
V
G
S
P
A
G
D
Chimpanzee
Pan troglodytes
XP_523393
405
44092
T216
S
S
R
G
R
I
V
T
V
G
S
P
A
G
D
Rhesus Macaque
Macaca mulatta
XP_001088119
491
53541
T302
S
S
R
G
R
I
V
T
V
G
S
P
A
G
D
Dog
Lupus familis
XP_853935
323
35433
L147
G
D
M
P
Y
P
C
L
A
A
Y
G
T
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P51661
386
42168
S210
L
L
P
L
L
R
H
S
R
G
R
I
V
T
V
Rat
Rattus norvegicus
P50233
400
43708
T216
H
S
R
G
R
I
V
T
V
G
S
P
A
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512268
333
36740
Q157
G
L
L
P
L
L
R
Q
S
Q
G
R
I
I
T
Chicken
Gallus gallus
Q5ZJZ5
339
38218
V163
T
Y
M
E
V
A
E
V
N
L
W
G
T
V
R
Frog
Xenopus laevis
Q0IH28
323
35135
M147
V
S
V
D
R
M
V
M
D
T
N
Y
F
G
P
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
R133
N
I
A
G
V
S
Y
R
G
N
I
L
D
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
V150
G
I
S
V
R
A
D
V
A
S
T
A
V
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130780
400
43694
T216
H
S
R
G
R
I
V
T
V
G
S
P
A
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
81
70.1
N.A.
82.9
85.6
N.A.
58.2
25.6
21.4
22.7
N.A.
21.4
N.A.
N.A.
N.A.
Protein Similarity:
100
100
81.4
75.8
N.A.
88.8
90.6
N.A.
66.9
41.4
37.5
35.3
N.A.
35.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
6.6
93.3
N.A.
0
0
26.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
0
N.A.
13.3
93.3
N.A.
6.6
6.6
40
13.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
85.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
90.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
17
0
0
17
9
0
9
42
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
9
0
9
0
0
0
9
9
42
% D
% Glu:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
25
0
0
50
0
0
0
0
9
50
9
17
0
50
0
% G
% His:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
0
17
0
0
0
42
0
0
0
0
9
9
9
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
9
17
9
9
17
9
0
9
0
9
0
9
0
0
0
% L
% Met:
0
0
17
0
0
9
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% N
% Pro:
0
0
9
17
0
9
0
0
0
0
0
42
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% Q
% Arg:
0
0
42
0
59
9
9
9
9
0
9
9
0
0
9
% R
% Ser:
25
50
9
0
0
9
0
9
9
9
42
0
0
9
0
% S
% Thr:
9
0
0
0
0
0
0
42
0
9
9
0
17
17
9
% T
% Val:
9
0
9
9
17
0
50
17
42
0
0
0
17
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
9
0
0
9
0
9
0
0
0
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _