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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IFI35
All Species:
29.09
Human Site:
S212
Identified Species:
71.11
UniProt:
P80217
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P80217
NP_005524.1
286
31514
S212
Q
Q
V
P
L
R
V
S
P
Y
V
N
G
E
I
Chimpanzee
Pan troglodytes
XP_001158983
288
31879
S214
Q
Q
V
P
L
R
V
S
P
Y
V
N
G
E
I
Rhesus Macaque
Macaca mulatta
XP_001112861
286
31664
S212
Q
Q
V
P
L
R
V
S
P
Y
V
N
G
E
I
Dog
Lupus familis
XP_548077
286
31831
S212
Q
S
F
P
L
R
V
S
P
Y
L
S
G
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8C4
286
31857
S212
Q
Q
V
L
L
R
V
S
P
Y
V
S
G
E
I
Rat
Rattus norvegicus
NP_001009625
286
31746
S212
Q
Q
V
L
L
R
V
S
P
Y
V
S
G
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516056
98
10789
G37
E
V
S
N
Q
E
L
G
H
L
Q
A
P
R
T
Chicken
Gallus gallus
XP_418132
383
43329
S307
T
K
Y
K
L
K
I
S
P
Y
M
S
G
D
V
Frog
Xenopus laevis
NP_001088598
383
44113
K309
V
L
H
Q
I
T
V
K
P
Y
I
D
M
K
L
Zebra Danio
Brachydanio rerio
XP_688060
371
42093
T291
R
K
Y
K
V
K
V
T
P
F
L
N
G
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
91.6
74.1
N.A.
72
72.7
N.A.
20.6
33.1
22.4
29.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
95.8
83.9
N.A.
84.2
84.6
N.A.
26.2
51.1
42.8
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
86.6
86.6
N.A.
0
33.3
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
13.3
80
53.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
0
0
0
0
60
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
80
0
0
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
70
% I
% Lys:
0
20
0
20
0
20
0
10
0
0
0
0
0
20
0
% K
% Leu:
0
10
0
20
70
0
10
0
0
10
20
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
40
0
0
0
% N
% Pro:
0
0
0
40
0
0
0
0
90
0
0
0
10
0
0
% P
% Gln:
60
50
0
10
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
0
0
0
0
60
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
10
0
0
0
0
70
0
0
0
40
0
0
0
% S
% Thr:
10
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% T
% Val:
10
10
50
0
10
0
80
0
0
0
50
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
80
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _