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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKDC All Species: 16.06
Human Site: T837 Identified Species: 39.26
UniProt: P78527 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78527 NP_001075109.1 4128 469089 T837 V L K H L K K T K N L S S N E
Chimpanzee Pan troglodytes XP_001147162 4128 468882 T837 V L K H L K K T K N L S S N E
Rhesus Macaque Macaca mulatta XP_001100610 4128 469402 T837 V L K H L K K T K N L S S N E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P97313 4128 471369 T836 V V K H L K R T R N S S P D E
Rat Rattus norvegicus NP_001101797 2098 241314
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514950 4153 474137 A857 V V R H L K K A K A T A P V E
Chicken Gallus gallus Q8QGX4 4134 472639 A833 V I Q R L R K A K T S S L D D
Frog Xenopus laevis Q9DEI1 4146 473487 M858 L I Q Q L K R M K T L S V K E
Zebra Danio Brachydanio rerio XP_001919588 4119 467204 S846 L L R L L K K S K R F S L G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781813 1817 205237
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 97.5 N.A. N.A. 79.1 39.2 N.A. 74.1 68.8 64 58.5 N.A. N.A. N.A. N.A. 20.8
Protein Similarity: 100 99.8 98.8 N.A. N.A. 88.7 44.7 N.A. 85.4 82.5 79.8 76.1 N.A. N.A. N.A. N.A. 31.6
P-Site Identity: 100 100 100 N.A. N.A. 60 0 N.A. 46.6 33.3 40 40 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 N.A. N.A. 86.6 0 N.A. 66.6 66.6 66.6 66.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 20 0 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 20 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 40 0 0 70 60 0 70 0 0 0 0 10 0 % K
% Leu: 20 40 0 10 80 0 0 0 0 0 40 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 40 0 0 0 30 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % P
% Gln: 0 0 20 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 20 10 0 10 20 0 10 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 20 70 30 0 0 % S
% Thr: 0 0 0 0 0 0 0 40 0 20 10 0 0 0 0 % T
% Val: 60 20 0 0 0 0 0 0 0 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _