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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKDC
All Species:
17.88
Human Site:
S2533
Identified Species:
43.7
UniProt:
P78527
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78527
NP_001075109.1
4128
469089
S2533
S
H
E
T
R
L
P
S
N
T
L
D
R
L
L
Chimpanzee
Pan troglodytes
XP_001147162
4128
468882
S2533
S
H
E
T
R
L
P
S
N
T
L
D
R
L
L
Rhesus Macaque
Macaca mulatta
XP_001100610
4128
469402
S2533
S
H
E
T
R
L
P
S
N
T
L
D
R
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97313
4128
471369
S2529
S
H
E
T
R
L
P
S
N
T
L
D
R
L
L
Rat
Rattus norvegicus
NP_001101797
2098
241314
E625
Y
Q
G
F
L
F
S
E
K
P
E
K
N
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514950
4153
474137
S2555
S
N
E
T
R
L
P
S
N
I
L
D
R
M
L
Chicken
Gallus gallus
Q8QGX4
4134
472639
N2533
D
E
T
R
L
P
A
N
I
L
D
R
M
L
M
Frog
Xenopus laevis
Q9DEI1
4146
473487
N2555
D
E
T
R
L
P
S
N
T
T
E
R
M
L
A
Zebra Danio
Brachydanio rerio
XP_001919588
4119
467204
E2541
H
E
S
R
L
P
P
E
T
L
E
R
M
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781813
1817
205237
Q344
A
C
K
F
E
E
V
Q
I
D
H
S
W
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
N.A.
N.A.
79.1
39.2
N.A.
74.1
68.8
64
58.5
N.A.
N.A.
N.A.
N.A.
20.8
Protein Similarity:
100
99.8
98.8
N.A.
N.A.
88.7
44.7
N.A.
85.4
82.5
79.8
76.1
N.A.
N.A.
N.A.
N.A.
31.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
6.6
N.A.
80
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
6.6
N.A.
93.3
20
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
0
10
10
50
0
0
0
% D
% Glu:
0
30
50
0
10
10
0
20
0
0
30
0
0
0
0
% E
% Phe:
0
0
0
20
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
40
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
40
50
0
0
0
20
50
0
0
80
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
30
10
10
% M
% Asn:
0
10
0
0
0
0
0
20
50
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
30
60
0
0
10
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
30
50
0
0
0
0
0
0
30
50
10
0
% R
% Ser:
50
0
10
0
0
0
20
50
0
0
0
10
0
0
0
% S
% Thr:
0
0
20
50
0
0
0
0
20
50
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _