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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX3
All Species:
14.85
Human Site:
S291
Identified Species:
29.7
UniProt:
P78415
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78415
NP_077312.2
501
52119
S291
P
I
S
D
S
K
N
S
D
S
E
D
S
S
E
Chimpanzee
Pan troglodytes
XP_510969
500
52128
S291
P
I
S
D
S
K
N
S
D
S
E
D
S
S
E
Rhesus Macaque
Macaca mulatta
XP_001092738
409
42853
G222
E
E
E
D
E
E
D
G
K
R
E
L
E
L
E
Dog
Lupus familis
XP_544403
503
52123
S292
P
I
A
D
S
K
N
S
D
S
D
D
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
P81067
507
52675
S294
P
I
S
D
C
K
T
S
D
S
D
D
S
S
E
Rat
Rattus norvegicus
NP_001100801
480
50115
G283
K
S
Q
D
S
P
L
G
L
A
K
E
V
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511678
479
51994
Q277
R
I
L
S
P
G
A
Q
G
G
L
Q
G
A
P
Chicken
Gallus gallus
Q9YGS0
485
52755
P296
P
P
P
R
A
A
E
P
P
A
A
A
A
E
E
Frog
Xenopus laevis
NP_001154863
495
55384
D295
R
Q
R
D
C
V
N
D
H
C
K
E
V
I
L
Zebra Danio
Brachydanio rerio
NP_571342
420
46871
S234
D
L
K
L
D
G
R
S
D
S
E
I
S
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54269
693
73649
C451
K
N
P
L
S
R
D
C
G
I
P
V
P
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
C191
Q
N
R
R
G
D
G
C
D
D
D
E
D
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
80.4
94.6
N.A.
91.1
41.1
N.A.
34.1
33.5
30.1
47.3
N.A.
25.6
N.A.
27.7
N.A.
Protein Similarity:
100
97.4
80.6
95.4
N.A.
92.6
54
N.A.
47.1
45.3
43.1
57.6
N.A.
36.6
N.A.
40.9
N.A.
P-Site Identity:
100
100
20
86.6
N.A.
80
26.6
N.A.
6.6
13.3
13.3
33.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
86.6
46.6
N.A.
13.3
33.3
26.6
40
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
9
9
0
0
17
9
9
9
17
0
% A
% Cys:
0
0
0
0
17
0
0
17
0
9
0
0
0
0
0
% C
% Asp:
9
0
0
59
9
9
17
9
50
9
25
34
9
17
9
% D
% Glu:
9
9
9
0
9
9
9
0
0
0
34
25
9
9
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
17
9
17
17
9
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
42
0
0
0
0
0
0
0
9
0
9
0
9
0
% I
% Lys:
17
0
9
0
0
34
0
0
9
0
17
0
0
0
0
% K
% Leu:
0
9
9
17
0
0
9
0
9
0
9
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
34
0
0
0
0
0
0
0
0
% N
% Pro:
42
9
17
0
9
9
0
9
9
0
9
0
9
0
9
% P
% Gln:
9
9
9
0
0
0
0
9
0
0
0
9
0
0
0
% Q
% Arg:
17
0
17
17
0
9
9
0
0
9
0
0
0
0
0
% R
% Ser:
0
9
25
9
42
0
0
42
0
42
0
0
42
42
9
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
9
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _