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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCT2
All Species:
48.79
Human Site:
S254
Identified Species:
71.56
UniProt:
P78371
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78371
NP_006422.1
535
57488
S254
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Chimpanzee
Pan troglodytes
XP_509216
616
65438
S335
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Rhesus Macaque
Macaca mulatta
XP_001108460
589
62930
S308
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Dog
Lupus familis
XP_531675
535
57413
S254
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P80314
535
57459
S254
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Rat
Rattus norvegicus
Q5XIM9
535
57440
S254
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511892
563
60802
S282
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Chicken
Gallus gallus
Q5ZJK8
553
60330
A265
N
T
V
E
D
Y
Q
A
I
V
D
A
E
W
N
Frog
Xenopus laevis
NP_001080388
535
57647
S254
D
K
I
K
V
F
G
S
R
V
R
V
D
S
T
Zebra Danio
Brachydanio rerio
NP_958863
535
57743
S254
D
K
I
K
I
F
G
S
R
V
R
V
D
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12613
557
59538
A268
D
K
L
E
A
I
R
A
R
E
L
D
I
T
K
Honey Bee
Apis mellifera
XP_393300
534
57884
S253
D
K
I
K
V
F
G
S
R
V
R
V
D
S
M
Nematode Worm
Caenorhab. elegans
P47207
529
56956
S248
D
K
V
K
V
F
G
S
R
V
R
V
D
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326179
527
57189
A249
D
K
V
K
I
Y
G
A
R
V
R
V
D
S
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28769
545
59211
A271
E
K
I
R
Q
R
E
A
D
M
T
K
E
R
I
Baker's Yeast
Sacchar. cerevisiae
P39076
527
57185
T248
D
K
V
K
I
F
G
T
K
F
K
V
D
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
90.8
98.3
N.A.
97.5
97.7
N.A.
91.3
34
90.2
87.4
N.A.
34.8
73.2
66.7
N.A.
Protein Similarity:
100
86.8
90.8
100
N.A.
99.2
99
N.A.
93.4
54
96
94.2
N.A.
57
86.9
80
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
93.3
100
N.A.
20
86.6
73.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
46.6
100
100
N.A.
46.6
93.3
86.6
N.A.
Percent
Protein Identity:
68
N.A.
N.A.
34.6
64.8
N.A.
Protein Similarity:
82.2
N.A.
N.A.
56.7
79.8
N.A.
P-Site Identity:
73.3
N.A.
N.A.
13.3
66.6
N.A.
P-Site Similarity:
93.3
N.A.
N.A.
46.6
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
25
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
88
0
0
0
7
0
0
0
7
0
7
7
82
0
0
% D
% Glu:
7
0
0
13
0
0
7
0
0
7
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
75
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
82
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
69
0
63
7
0
0
7
0
0
0
7
0
7
% I
% Lys:
0
94
0
82
0
0
0
0
7
0
7
7
0
0
7
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
13
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
7
7
0
82
0
75
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
69
0
0
0
0
0
75
0
% S
% Thr:
0
7
0
0
0
0
0
7
0
0
7
0
0
7
63
% T
% Val:
0
0
25
0
19
0
0
0
0
82
0
82
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _