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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN10
All Species:
8.59
Human Site:
Y227
Identified Species:
23.61
UniProt:
P78369
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78369
NP_008915.1
228
24488
Y227
K
Q
F
D
K
N
A
Y
V
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_519278
194
20690
Rhesus Macaque
Macaca mulatta
XP_001086030
228
24440
Y227
K
Q
F
D
K
N
A
Y
V
_
_
_
_
_
_
Dog
Lupus familis
XP_534163
231
24683
K227
N
P
S
K
Q
F
D
K
N
A
Y
V
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S6
231
24674
K227
G
P
S
K
Q
F
D
K
N
A
Y
V
_
_
_
Rat
Rattus norvegicus
Q5QT56
224
23297
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512470
236
25803
K232
S
P
P
K
Q
F
D
K
N
A
Y
V
_
_
_
Chicken
Gallus gallus
XP_416985
228
24353
Y227
K
H
F
D
K
N
A
Y
V
_
_
_
_
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9YH92
215
22846
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.1
99.5
95.6
N.A.
92.6
37.7
N.A.
62.2
80.6
N.A.
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57
99.5
96.5
N.A.
96
57.4
N.A.
70.7
90.7
N.A.
51.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
0
88.8
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
16.6
N.A.
16.6
0
N.A.
16.6
88.8
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
34
0
0
34
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
0
0
34
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
34
0
0
34
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
0
34
34
0
0
34
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
34
0
0
34
0
0
0
0
0
0
% N
% Pro:
0
34
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
23
0
0
34
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
34
0
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
34
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
34
34
34
67
67
67
% _