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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLDN10 All Species: 4.24
Human Site: Y192 Identified Species: 11.67
UniProt: P78369 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78369 NP_008915.1 228 24488 Y192 D N N K T P R Y T Y N G A T S
Chimpanzee Pan troglodytes XP_519278 194 20690 G159 P G T K Y E L G P A L Y L G W
Rhesus Macaque Macaca mulatta XP_001086030 228 24440 Y192 D N N K T P R Y A Y N G A T S
Dog Lupus familis XP_534163 231 24683 M192 D N N K P P R M G Y A Y N G A
Cat Felis silvestris
Mouse Mus musculus Q9Z0S6 231 24674 M192 D N N K T P R M G Y T Y N G P
Rat Rattus norvegicus Q5QT56 224 23297 P189 L C C T C P E P E R A N S I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512470 236 25803 M197 E G N K S P R M G Y A Y N G A
Chicken Gallus gallus XP_416985 228 24353 R192 E N S K S P R R A Y A Y N G A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9YH92 215 22846 G180 F L D I M G G G M L A S S C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.1 99.5 95.6 N.A. 92.6 37.7 N.A. 62.2 80.6 N.A. 35.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57 99.5 96.5 N.A. 96 57.4 N.A. 70.7 90.7 N.A. 51.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 46.6 N.A. 53.3 6.6 N.A. 33.3 33.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 93.3 53.3 N.A. 53.3 13.3 N.A. 53.3 60 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 23 12 56 0 23 0 34 % A
% Cys: 0 12 12 0 12 0 0 0 0 0 0 0 0 12 0 % C
% Asp: 45 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 23 0 0 0 0 12 12 0 12 0 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 23 0 0 0 12 12 23 34 0 0 23 0 56 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 0 0 0 78 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 12 0 0 0 0 12 0 0 12 12 0 12 0 0 % L
% Met: 0 0 0 0 12 0 0 34 12 0 0 0 0 0 0 % M
% Asn: 0 56 56 0 0 0 0 0 0 0 23 12 45 0 0 % N
% Pro: 12 0 0 0 12 78 0 12 12 0 0 0 0 0 23 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 67 12 0 12 0 0 0 0 0 % R
% Ser: 0 0 12 0 23 0 0 0 0 0 0 12 23 0 34 % S
% Thr: 0 0 12 12 34 0 0 0 12 0 12 0 0 23 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % W
% Tyr: 0 0 0 0 12 0 0 23 0 67 0 56 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _