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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
10.91
Human Site:
Y483
Identified Species:
21.82
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
Y483
E
A
I
L
N
F
L
Y
K
G
P
R
E
S
Q
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
Y556
E
A
I
L
N
F
L
Y
K
G
P
R
E
N
Q
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
E444
G
V
V
F
L
G
P
E
D
S
S
D
P
T
E
Dog
Lupus familis
XP_538773
2261
253895
A468
K
D
I
L
A
F
L
A
K
H
P
E
D
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
S483
E
A
V
L
N
F
F
S
N
G
P
Q
E
K
Q
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
L460
T
T
T
G
P
G
H
L
R
V
K
I
R
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
A473
R
D
I
V
A
F
L
A
K
H
P
E
D
H
Q
Chicken
Gallus gallus
XP_422330
2276
256293
H482
E
Y
I
I
N
F
L
H
N
G
P
P
G
S
R
Frog
Xenopus laevis
NP_001089022
2363
267334
Y483
D
D
I
I
N
F
L
Y
N
G
N
P
D
E
R
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
H483
K
D
I
L
N
F
L
H
N
G
P
E
G
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
R86
I
Y
K
R
W
C
L
R
S
D
V
V
V
G
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
R264
R
M
V
P
F
P
T
R
E
Y
T
D
D
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
93.3
0
46.6
N.A.
60
0
N.A.
40
53.3
40
46.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
20
60
N.A.
73.3
6.6
N.A.
53.3
73.3
66.6
66.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
17
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
34
0
0
0
0
0
0
9
9
0
17
34
0
9
% D
% Glu:
34
0
0
0
0
0
0
9
9
0
0
25
25
25
9
% E
% Phe:
0
0
0
9
9
67
9
0
0
0
0
0
0
0
9
% F
% Gly:
9
0
0
9
0
17
0
0
0
50
0
0
17
9
0
% G
% His:
0
0
0
0
0
0
9
17
0
17
0
0
0
9
0
% H
% Ile:
9
0
59
17
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
17
0
9
0
0
0
0
0
34
0
9
0
0
9
0
% K
% Leu:
0
0
0
42
9
0
67
9
0
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
50
0
0
0
34
0
9
0
0
9
0
% N
% Pro:
0
0
0
9
9
9
9
0
0
0
59
17
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
42
% Q
% Arg:
17
0
0
9
0
0
0
17
9
0
0
17
9
0
25
% R
% Ser:
0
0
0
0
0
0
0
9
9
9
9
0
0
17
0
% S
% Thr:
9
9
9
0
0
0
9
0
0
0
9
0
0
9
0
% T
% Val:
0
9
25
9
0
0
0
0
0
9
9
9
9
9
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
25
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _