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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 30.3
Human Site: Y1947 Identified Species: 60.61
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 Y1947 L H E L T K I Y P G T S S P A
Chimpanzee Pan troglodytes XP_001152577 2346 264166 Y2020 L H E L T K I Y P G T S S P A
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 Y1804 L R N L T K V Y H G Q R M P A
Dog Lupus familis XP_538773 2261 253895 Y1921 I K E L T K I Y R R K R K P A
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 Y1946 L N E L T K V Y S G S S S P A
Rat Rattus norvegicus Q7TNJ2 2170 237702 Y1827 L R D L T K V Y R G Q R S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 Y1926 I K E L T K V Y R M K R K P A
Chicken Gallus gallus XP_422330 2276 256293 Y1940 L Q E L T K I Y A G R H K P A
Frog Xenopus laevis NP_001089022 2363 267334 Y2026 L K E L T K T Y P G K Q S P A
Zebra Danio Brachydanio rerio XP_683123 2330 265308 Y1992 I R D L S K T Y R R R K R P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 E1405 C L A V D Q K E C F G L L G V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 S1583 E F D L L K H S H K P S F T L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 100 53.3 53.3 N.A. 73.3 60 N.A. 46.6 66.6 73.3 33.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 60 60 N.A. 93.3 73.3 N.A. 60 66.6 73.3 53.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 84 % A
% Cys: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 25 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 59 0 0 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 9 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 59 9 0 0 9 0 % G
% His: 0 17 0 0 0 0 9 0 17 0 0 9 0 0 0 % H
% Ile: 25 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % I
% Lys: 0 25 0 0 0 92 9 0 0 9 25 9 25 0 0 % K
% Leu: 59 9 0 92 9 0 0 0 0 0 0 9 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % M
% Asn: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 25 0 9 0 0 84 0 % P
% Gln: 0 9 0 0 0 9 0 0 0 0 17 9 0 0 0 % Q
% Arg: 0 25 0 0 0 0 0 0 34 17 17 34 9 0 0 % R
% Ser: 0 0 0 0 9 0 0 9 9 0 9 34 42 0 0 % S
% Thr: 0 0 0 0 75 0 17 0 0 0 17 0 0 9 0 % T
% Val: 0 0 0 9 0 0 34 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _