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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
13.94
Human Site:
T901
Identified Species:
27.88
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
T901
L
E
K
T
E
P
L
T
E
E
T
E
D
P
E
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
T974
L
E
K
T
E
P
L
T
E
E
T
E
D
P
E
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
G856
T
T
L
S
I
L
S
G
L
F
P
P
S
G
G
Dog
Lupus familis
XP_538773
2261
253895
I886
S
Q
K
G
V
S
E
I
C
M
E
E
E
P
T
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
T901
L
E
K
T
E
P
L
T
E
E
M
E
D
P
E
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
V870
A
S
I
L
G
H
D
V
Q
T
N
M
A
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
I891
S
R
K
G
A
S
E
I
C
V
E
E
E
P
S
Chicken
Gallus gallus
XP_422330
2276
256293
T900
G
E
R
N
E
S
R
T
K
K
S
E
E
P
E
Frog
Xenopus laevis
NP_001089022
2363
267334
H901
V
Q
T
E
L
S
I
H
E
H
V
E
E
N
H
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
H901
P
E
K
P
L
E
N
H
V
E
K
Q
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Q496
Q
N
T
R
I
N
E
Q
V
R
N
R
V
R
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
S674
M
A
E
E
V
G
L
S
D
K
I
N
T
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
0
20
N.A.
93.3
0
N.A.
20
40
13.3
20
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
6.6
33.3
N.A.
93.3
6.6
N.A.
26.6
73.3
40
33.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
0
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
0
0
25
9
0
% D
% Glu:
0
42
9
17
34
9
25
0
34
34
17
59
42
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
17
9
9
0
9
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
9
0
17
0
9
0
0
0
0
9
% H
% Ile:
0
0
9
0
17
0
9
17
0
0
9
0
0
0
9
% I
% Lys:
0
0
50
0
0
0
0
0
9
17
9
0
0
0
0
% K
% Leu:
25
0
9
9
17
9
34
0
9
0
0
0
0
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
9
9
9
0
0
0
% M
% Asn:
0
9
0
9
0
9
9
0
0
0
17
9
0
9
0
% N
% Pro:
9
0
0
9
0
25
0
0
0
0
9
9
0
50
0
% P
% Gln:
9
17
0
0
0
0
0
9
9
0
0
9
0
0
0
% Q
% Arg:
0
9
9
9
0
0
9
0
0
9
0
9
0
9
9
% R
% Ser:
17
9
0
9
0
34
9
9
0
0
9
0
9
0
9
% S
% Thr:
9
9
17
25
0
0
0
34
0
9
17
0
9
0
9
% T
% Val:
9
0
0
0
17
0
0
9
17
9
9
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _