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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
20.91
Human Site:
T454
Identified Species:
41.82
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
T454
Q
M
N
M
I
R
D
T
L
G
N
P
T
V
K
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
T527
Q
M
N
M
I
R
D
T
L
G
N
P
T
V
K
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
A415
S
L
D
K
L
E
A
A
P
S
E
A
A
L
V
Dog
Lupus familis
XP_538773
2261
253895
L439
E
M
D
L
V
R
T
L
L
D
S
R
S
N
D
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
T454
Q
M
T
V
I
R
D
T
L
Q
H
P
T
V
K
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
L431
E
L
L
G
E
R
R
L
W
A
G
I
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
L444
E
M
D
L
I
R
T
L
L
G
N
K
G
N
S
Chicken
Gallus gallus
XP_422330
2276
256293
S453
Q
M
N
M
I
R
D
S
L
K
H
S
T
V
R
Frog
Xenopus laevis
NP_001089022
2363
267334
T454
Q
M
N
I
V
R
D
T
I
K
N
P
T
V
K
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
T454
Q
M
N
M
I
R
D
T
L
R
N
P
T
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Y57
T
S
S
P
E
N
I
Y
D
N
F
Q
V
K
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
H235
N
N
D
L
P
L
S
H
S
N
L
S
S
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
0
20
N.A.
73.3
6.6
N.A.
40
66.6
73.3
86.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
26.6
60
N.A.
86.6
20
N.A.
60
86.6
93.3
86.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
9
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
50
0
9
9
0
0
0
0
9
% D
% Glu:
25
0
0
0
17
9
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
25
9
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
0
% H
% Ile:
0
0
0
9
50
0
9
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
17
0
9
0
9
34
% K
% Leu:
0
17
9
25
9
9
0
25
59
0
9
0
0
9
17
% L
% Met:
0
67
0
34
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
9
42
0
0
9
0
0
0
17
42
0
0
17
0
% N
% Pro:
0
0
0
9
9
0
0
0
9
0
0
42
0
0
0
% P
% Gln:
50
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
75
9
0
0
9
0
9
0
0
9
% R
% Ser:
9
9
9
0
0
0
9
9
9
9
9
17
17
0
9
% S
% Thr:
9
0
9
0
0
0
17
42
0
0
0
0
50
0
0
% T
% Val:
0
0
0
9
17
0
0
0
0
0
0
0
17
50
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _