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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
10.61
Human Site:
T1196
Identified Species:
21.21
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
T1196
P
A
H
V
D
D
L
T
P
E
Q
V
L
D
G
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
T1269
P
A
H
V
D
D
L
T
P
E
Q
V
L
D
G
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
L1124
F
Q
E
L
D
T
R
L
A
E
L
S
L
T
G
Dog
Lupus familis
XP_538773
2261
253895
L1167
Q
S
S
S
D
A
G
L
G
S
D
H
E
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
T1196
P
T
R
V
D
E
I
T
E
E
Q
V
L
D
G
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
T1134
A
L
D
G
S
F
A
T
V
F
Q
E
L
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
L1171
Q
S
S
S
D
A
G
L
G
S
D
H
E
S
D
Chicken
Gallus gallus
XP_422330
2276
256293
Q1195
L
M
D
K
E
G
T
Q
E
Q
E
L
G
G
D
Frog
Xenopus laevis
NP_001089022
2363
267334
P1264
T
P
K
A
K
E
D
P
L
E
Q
E
L
D
G
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
L1247
Y
K
E
E
S
Q
A
L
Q
P
E
R
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
T760
G
K
L
V
A
S
G
T
N
Q
Y
L
K
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
W938
R
L
I
V
A
A
V
W
T
L
I
G
F
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
26.6
6.6
N.A.
66.6
26.6
N.A.
6.6
0
33.3
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
33.3
13.3
N.A.
80
26.6
N.A.
13.3
26.6
40
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
9
17
25
17
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
50
17
9
0
0
0
17
0
0
42
34
% D
% Glu:
0
0
17
9
9
17
0
0
17
42
17
17
17
0
0
% E
% Phe:
9
0
0
0
0
9
0
0
0
9
0
0
9
0
0
% F
% Gly:
9
0
0
9
0
9
25
0
17
0
0
9
9
9
42
% G
% His:
0
0
17
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
0
0
9
0
0
9
0
% I
% Lys:
0
17
9
9
9
0
0
0
0
0
0
0
9
0
9
% K
% Leu:
9
17
9
9
0
0
17
34
9
9
9
17
50
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
25
9
0
0
0
0
0
9
17
9
0
0
0
0
0
% P
% Gln:
17
9
0
0
0
9
0
9
9
17
42
0
0
9
9
% Q
% Arg:
9
0
9
0
0
0
9
0
0
0
0
9
0
0
0
% R
% Ser:
0
17
17
17
17
9
0
0
0
17
0
9
0
17
9
% S
% Thr:
9
9
0
0
0
9
9
42
9
0
0
0
0
9
0
% T
% Val:
0
0
0
42
0
0
9
0
9
0
0
25
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _