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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 6.06
Human Site: S997 Identified Species: 12.12
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 S997 G G R D I E T S L D A V R Q S
Chimpanzee Pan troglodytes XP_001152577 2346 264166 S1070 G G R D I E T S L D A V R Q S
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 S934 V G L V S K Q S V Q T R H L S
Dog Lupus familis XP_538773 2261 253895 E967 L G K D I R F E M N T I R Q N
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 N997 G G K D I E T N L D V V R Q S
Rat Rattus norvegicus Q7TNJ2 2170 237702 K945 L S G G M Q R K L S V A I A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 E972 L G K D I R S E L S T I R Q N
Chicken Gallus gallus XP_422330 2276 256293 H996 G G L D I Q T H M D S I R Q R
Frog Xenopus laevis NP_001089022 2363 267334 H1065 R G R D I Q T H M D S I R Q S
Zebra Danio Brachydanio rerio XP_683123 2330 265308 E1048 Y G R D I R T E M D A I R Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 V571 D G L S L R A V R G Q C S I L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 G749 M D E A E E L G D R I G I M A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 100 20 33.3 N.A. 80 6.6 N.A. 40 53.3 60 66.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 33.3 66.6 N.A. 93.3 20 N.A. 66.6 80 86.6 80 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 9 0 0 0 25 9 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 9 0 67 0 0 0 0 9 50 0 0 0 0 0 % D
% Glu: 0 0 9 0 9 34 0 25 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % F
% Gly: 34 84 9 9 0 0 0 9 0 9 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 17 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 67 0 0 0 0 0 9 42 17 9 0 % I
% Lys: 0 0 25 0 0 9 0 9 0 0 0 0 0 0 0 % K
% Leu: 25 0 25 0 9 0 9 0 42 0 0 0 0 9 9 % L
% Met: 9 0 0 0 9 0 0 0 34 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 17 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 25 9 0 0 9 9 0 0 67 0 % Q
% Arg: 9 0 34 0 0 34 9 0 9 9 0 9 67 0 9 % R
% Ser: 0 9 0 9 9 0 9 25 0 17 17 0 9 0 50 % S
% Thr: 0 0 0 0 0 0 50 0 0 0 25 0 0 0 0 % T
% Val: 9 0 0 9 0 0 0 9 9 0 17 25 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _