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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
36.67
Human Site:
S2235
Identified Species:
73.33
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
S2235
S
L
L
I
E
E
Y
S
V
T
Q
T
T
L
D
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
S2308
S
L
L
I
E
E
Y
S
V
T
Q
T
T
L
D
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
S2089
E
H
G
V
E
D
F
S
V
S
Q
T
M
L
E
Dog
Lupus familis
XP_538773
2261
253895
S2207
R
L
H
I
E
D
Y
S
V
S
Q
T
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
S2234
S
L
L
I
E
E
Y
S
V
T
Q
T
T
L
D
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
S2112
A
H
G
V
E
D
F
S
V
S
Q
T
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S2212
R
L
H
I
E
D
Y
S
V
S
Q
T
T
L
D
Chicken
Gallus gallus
XP_422330
2276
256293
S2228
N
L
Y
I
E
E
Y
S
V
S
Q
T
T
L
D
Frog
Xenopus laevis
NP_001089022
2363
267334
S2314
S
L
N
I
E
E
Y
S
V
S
Q
T
T
L
D
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
S2280
R
L
N
I
E
D
Y
S
V
S
Q
T
T
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
D1667
A
K
D
L
G
V
K
D
F
I
L
A
Q
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
L1845
F
G
E
G
G
L
S
L
A
D
A
F
G
H
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
40
73.3
N.A.
100
46.6
N.A.
73.3
80
86.6
73.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
73.3
86.6
N.A.
100
86.6
N.A.
86.6
93.3
93.3
86.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
42
0
9
0
9
0
0
0
0
67
% D
% Glu:
9
0
9
0
84
42
0
0
0
0
0
0
0
0
17
% E
% Phe:
9
0
0
0
0
0
17
0
9
0
0
9
0
0
0
% F
% Gly:
0
9
17
9
17
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
17
17
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
67
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
25
9
0
9
0
9
0
0
9
0
0
84
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
84
0
9
0
0
% Q
% Arg:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
0
0
0
0
0
9
84
0
59
0
0
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
25
0
84
75
0
0
% T
% Val:
0
0
0
17
0
9
0
0
84
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
67
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _