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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 21.82
Human Site: S1487 Identified Species: 43.64
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 S1487 T Q V N P S P S C R C S T R E
Chimpanzee Pan troglodytes XP_001152577 2346 264166 S1560 T Q A N P S P S C R C S T R E
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 D1346 T P E S P S P D C Q C S Q P G
Dog Lupus familis XP_538773 2261 253895 T1462 T M E N P S P T C Q C S S D K
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 S1486 T A A H P S P S C K C S T R E
Rat Rattus norvegicus Q7TNJ2 2170 237702 A1369 T P D S P S P A C Q C S Q P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 A1467 T M E N P S P A C E C S N D K
Chicken Gallus gallus XP_422330 2276 256293 S1480 S S E N P S P S C K C S T H K
Frog Xenopus laevis NP_001089022 2363 267334 S1566 T R D N P S P S C T C S T R S
Zebra Danio Brachydanio rerio XP_683123 2330 265308 S1529 D S R N P S P S C E C S T D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 L980 L L G L V G S L T T L K S N N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 H1158 M T I Q T R N H P L P P T K T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 93.3 46.6 53.3 N.A. 73.3 46.6 N.A. 53.3 60 73.3 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 93.3 60 80 N.A. 86.6 66.6 N.A. 66.6 80 80 60 N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 0 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 84 0 84 0 0 0 0 % C
% Asp: 9 0 17 0 0 0 0 9 0 0 0 0 0 25 0 % D
% Glu: 0 0 34 0 0 0 0 0 0 17 0 0 0 0 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 17 % G
% His: 0 0 0 9 0 0 0 9 0 0 0 0 0 9 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 17 0 9 0 9 25 % K
% Leu: 9 9 0 9 0 0 0 9 0 9 9 0 0 0 9 % L
% Met: 9 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 59 0 0 9 0 0 0 0 0 9 9 9 % N
% Pro: 0 17 0 0 84 0 84 0 9 0 9 9 0 17 0 % P
% Gln: 0 17 0 9 0 0 0 0 0 25 0 0 17 0 0 % Q
% Arg: 0 9 9 0 0 9 0 0 0 17 0 0 0 34 0 % R
% Ser: 9 17 0 17 0 84 9 50 0 0 0 84 17 0 9 % S
% Thr: 67 9 0 0 9 0 0 9 9 17 0 0 59 0 9 % T
% Val: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _