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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
4.55
Human Site:
S1173
Identified Species:
9.09
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
S1173
I
Q
S
Q
R
K
G
S
E
G
T
C
S
C
S
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
S1246
I
Q
S
Q
R
K
G
S
E
G
T
C
S
C
S
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
L1101
E
L
P
H
E
L
V
L
V
L
P
Y
T
G
A
Dog
Lupus familis
XP_538773
2261
253895
N1144
S
S
L
S
S
C
R
N
S
S
S
T
V
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
C1173
I
Q
S
Q
R
G
G
C
E
G
V
C
S
C
T
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
V1111
H
V
P
G
A
Q
L
V
E
E
L
P
H
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
N1148
S
S
L
S
S
C
R
N
S
S
S
T
V
S
Y
Chicken
Gallus gallus
XP_422330
2276
256293
L1172
T
R
T
G
R
S
S
L
C
S
C
G
S
Q
C
Frog
Xenopus laevis
NP_001089022
2363
267334
D1241
I
K
D
T
G
K
K
D
S
A
S
C
R
S
D
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
C1224
Q
R
K
K
E
N
E
C
D
C
A
S
E
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
M737
I
L
L
T
T
H
Y
M
D
E
A
E
R
L
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
C915
Q
P
K
L
L
A
S
C
N
D
G
A
G
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
0
0
N.A.
73.3
6.6
N.A.
0
13.3
20
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
80
13.3
N.A.
13.3
26.6
33.3
33.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
0
9
17
9
0
0
9
% A
% Cys:
0
0
0
0
0
17
0
25
9
9
9
34
0
34
9
% C
% Asp:
0
0
9
0
0
0
0
9
17
9
0
0
0
0
9
% D
% Glu:
9
0
0
0
17
0
9
0
34
17
0
9
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
9
9
25
0
0
25
9
9
9
9
9
% G
% His:
9
0
0
9
0
9
0
0
0
0
0
0
9
0
0
% H
% Ile:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
9
17
9
0
25
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
17
25
9
9
9
9
17
0
9
9
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
17
9
0
0
0
0
0
0
% N
% Pro:
0
9
17
0
0
0
0
0
0
0
9
9
0
0
0
% P
% Gln:
17
25
0
25
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
17
0
0
34
0
17
0
0
0
0
0
17
0
0
% R
% Ser:
17
17
25
17
17
9
17
17
25
25
25
9
34
25
25
% S
% Thr:
9
0
9
17
9
0
0
0
0
0
17
17
9
0
9
% T
% Val:
0
9
0
0
0
0
9
9
9
0
9
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _