KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PITX1
All Species:
27.88
Human Site:
S222
Identified Species:
68.15
UniProt:
P78337
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78337
NP_002644.4
314
34128
S222
S
A
P
S
S
I
S
S
M
T
M
P
S
S
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110089
314
34245
S222
S
A
P
S
S
I
S
S
M
T
M
P
S
S
M
Dog
Lupus familis
XP_850773
313
33972
S221
S
A
P
S
S
I
S
S
M
T
M
P
S
S
M
Cat
Felis silvestris
Mouse
Mus musculus
P70314
315
34056
S223
S
A
P
S
S
I
S
S
M
T
M
P
S
S
M
Rat
Rattus norvegicus
Q99NA7
315
34189
S223
S
A
P
S
S
I
S
S
M
T
M
P
S
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P56673
311
34455
S220
S
A
P
S
S
I
S
S
M
N
M
P
S
G
M
Frog
Xenopus laevis
Q9W751
305
34109
M213
S
S
I
S
S
M
S
M
P
S
S
M
G
H
S
Zebra Danio
Brachydanio rerio
Q9W5Z2
314
35169
S216
S
P
P
N
S
I
S
S
M
S
M
S
S
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O18400
509
53198
S402
N
C
F
N
T
G
A
S
G
V
A
V
S
M
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52906
323
36184
Q231
G
Y
G
G
A
W
Q
Q
N
P
Y
Y
S
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
98.4
N.A.
96.5
95.5
N.A.
N.A.
82.4
80.5
60.5
N.A.
30
N.A.
30.6
N.A.
Protein Similarity:
100
N.A.
98.4
98.7
N.A.
97.7
97.1
N.A.
N.A.
87.2
86.6
70.3
N.A.
40.6
N.A.
45.2
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
26.6
73.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
46.6
86.6
N.A.
40
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
10
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
10
0
10
0
0
10
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
0
70
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
10
70
0
70
10
0
10
70
% M
% Asn:
10
0
0
20
0
0
0
0
10
10
0
0
0
0
20
% N
% Pro:
0
10
70
0
0
0
0
0
10
10
0
60
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
80
10
0
70
80
0
80
80
0
20
10
10
90
60
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
50
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _