KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC1
All Species:
39.7
Human Site:
Y428
Identified Species:
51.37
UniProt:
P62191
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62191
NP_002793.2
440
49185
Y428
K
S
K
E
N
V
L
Y
K
K
Q
E
G
T
P
Chimpanzee
Pan troglodytes
XP_001142567
399
44420
D388
D
D
L
I
M
A
K
D
D
L
S
G
A
D
I
Rhesus Macaque
Macaca mulatta
XP_001103312
440
49180
Y428
K
S
K
E
N
V
L
Y
K
K
Q
E
G
T
P
Dog
Lupus familis
XP_848524
440
49333
Y428
K
S
K
E
N
V
L
Y
R
K
Q
E
G
T
P
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
F399
Y
I
V
L
A
K
D
F
E
K
A
Y
K
T
V
Rat
Rattus norvegicus
P62193
440
49166
Y428
K
S
K
E
N
V
L
Y
K
K
Q
E
G
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517805
388
43713
K377
S
K
E
N
V
L
Y
K
K
Q
E
G
T
P
E
Chicken
Gallus gallus
Q90732
440
49185
Y428
K
S
K
E
N
F
L
Y
K
K
T
E
G
T
P
Frog
Xenopus laevis
P46470
461
52229
L445
I
I
T
N
S
Y
H
L
Q
I
F
K
P
T
I
Zebra Danio
Brachydanio rerio
NP_001002091
440
49193
Y428
K
S
K
E
N
V
L
Y
K
K
Q
E
G
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
Y427
K
S
K
E
S
V
L
Y
R
K
K
E
G
T
P
Honey Bee
Apis mellifera
XP_623527
440
49215
Y428
K
S
K
E
S
V
L
Y
R
K
K
E
G
S
P
Nematode Worm
Caenorhab. elegans
O16368
443
49704
Y431
K
S
K
E
N
V
L
Y
R
K
K
E
G
A
P
Sea Urchin
Strong. purpuratus
XP_796230
443
49683
Y431
K
S
K
E
N
V
L
Y
R
K
T
E
G
T
P
Poplar Tree
Populus trichocarpa
XP_002301829
446
49676
F434
K
A
K
E
K
V
M
F
K
K
K
E
G
V
P
Maize
Zea mays
NP_001146268
446
49429
F434
K
A
K
E
K
V
M
F
K
K
K
E
G
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL67
443
49328
F431
K
A
K
E
K
V
M
F
K
K
K
E
G
V
P
Baker's Yeast
Sacchar. cerevisiae
P40327
437
48810
K425
Q
A
K
E
R
V
M
K
N
K
V
E
E
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
99.7
97
N.A.
45
100
N.A.
88.1
98.6
42.2
97.2
N.A.
91.3
91.8
83
89.6
Protein Similarity:
100
90.4
100
98.1
N.A.
68.1
100
N.A.
88.1
99
60
99.5
N.A.
95.9
96.3
92.7
95.2
P-Site Identity:
100
0
100
93.3
N.A.
13.3
100
N.A.
6.6
86.6
6.6
100
N.A.
80
73.3
80
86.6
P-Site Similarity:
100
0
100
100
N.A.
26.6
100
N.A.
33.3
86.6
26.6
100
N.A.
100
100
93.3
93.3
Percent
Protein Identity:
77.3
76
N.A.
77.4
71.3
N.A.
Protein Similarity:
90.5
90.3
N.A.
90.5
85.6
N.A.
P-Site Identity:
60
60
N.A.
60
33.3
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
6
6
0
0
0
0
6
0
6
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
0
0
0
0
6
6
6
0
0
0
0
6
0
% D
% Glu:
0
0
6
78
0
0
0
0
6
0
6
78
6
0
6
% E
% Phe:
0
0
0
0
0
6
0
23
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
73
0
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
6
12
0
6
0
0
0
0
0
6
0
0
0
0
12
% I
% Lys:
73
6
78
0
17
6
6
12
50
84
34
6
6
0
0
% K
% Leu:
0
0
6
6
0
6
56
6
0
6
0
0
0
0
6
% L
% Met:
0
0
0
0
6
0
23
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
45
0
0
0
6
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
6
6
73
% P
% Gln:
6
0
0
0
0
0
0
0
6
6
28
0
0
0
0
% Q
% Arg:
0
0
0
0
6
0
0
0
28
0
0
0
0
0
0
% R
% Ser:
6
56
0
0
17
0
0
0
0
0
6
0
0
6
0
% S
% Thr:
0
0
6
0
0
0
0
0
0
0
12
0
6
56
0
% T
% Val:
0
0
6
0
6
73
0
0
0
0
6
0
0
17
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
6
6
56
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _