KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC1
All Species:
56.97
Human Site:
Y225
Identified Species:
73.73
UniProt:
P62191
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62191
NP_002793.2
440
49185
Y225
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Chimpanzee
Pan troglodytes
XP_001142567
399
44420
K198
D
N
Q
I
Q
E
I
K
E
S
V
E
L
P
L
Rhesus Macaque
Macaca mulatta
XP_001103312
440
49180
Y225
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Dog
Lupus familis
XP_848524
440
49333
Y225
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
G206
P
R
G
V
L
M
Y
G
P
P
G
C
G
K
T
Rat
Rattus norvegicus
P62193
440
49166
Y225
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517805
388
43713
N189
L
L
A
K
A
V
A
N
Q
T
S
A
T
F
L
Chicken
Gallus gallus
Q90732
440
49185
Y225
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Frog
Xenopus laevis
P46470
461
52229
F218
G
S
E
L
V
Q
K
F
I
G
E
G
A
R
M
Zebra Danio
Brachydanio rerio
NP_001002091
440
49193
Y225
P
P
K
G
V
I
L
Y
G
A
P
G
T
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
Y224
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Honey Bee
Apis mellifera
XP_623527
440
49215
Y225
P
P
K
G
V
I
L
Y
G
P
P
G
T
G
K
Nematode Worm
Caenorhab. elegans
O16368
443
49704
Y228
P
P
K
G
V
I
L
Y
G
C
P
G
T
G
K
Sea Urchin
Strong. purpuratus
XP_796230
443
49683
Y228
P
P
K
G
V
I
L
Y
G
A
P
G
T
G
K
Poplar Tree
Populus trichocarpa
XP_002301829
446
49676
Y231
P
P
K
G
V
I
L
Y
G
E
P
G
T
G
K
Maize
Zea mays
NP_001146268
446
49429
Y231
P
P
K
G
V
I
L
Y
G
E
P
G
T
G
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL67
443
49328
Y228
P
P
K
G
V
I
L
Y
G
E
P
G
T
G
K
Baker's Yeast
Sacchar. cerevisiae
P40327
437
48810
Y222
P
P
K
G
V
I
L
Y
G
A
P
G
T
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
99.7
97
N.A.
45
100
N.A.
88.1
98.6
42.2
97.2
N.A.
91.3
91.8
83
89.6
Protein Similarity:
100
90.4
100
98.1
N.A.
68.1
100
N.A.
88.1
99
60
99.5
N.A.
95.9
96.3
92.7
95.2
P-Site Identity:
100
0
100
100
N.A.
13.3
100
N.A.
6.6
100
13.3
93.3
N.A.
100
100
93.3
93.3
P-Site Similarity:
100
13.3
100
100
N.A.
26.6
100
N.A.
13.3
100
26.6
93.3
N.A.
100
100
93.3
93.3
Percent
Protein Identity:
77.3
76
N.A.
77.4
71.3
N.A.
Protein Similarity:
90.5
90.3
N.A.
90.5
85.6
N.A.
P-Site Identity:
93.3
93.3
N.A.
93.3
93.3
N.A.
P-Site Similarity:
93.3
93.3
N.A.
93.3
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
6
0
6
0
0
17
0
6
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
6
0
0
0
% C
% Asp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
6
0
0
6
0
0
6
17
6
6
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
6
0
% F
% Gly:
6
0
6
78
0
0
0
6
78
6
6
84
6
78
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
78
6
0
6
0
0
0
0
0
0
% I
% Lys:
0
0
78
6
0
0
6
6
0
0
0
0
0
6
78
% K
% Leu:
6
6
0
6
6
0
78
0
0
0
0
0
6
0
12
% L
% Met:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
6
0
0
0
0
0
6
0
0
0
0
0
0
0
% N
% Pro:
84
78
0
0
0
0
0
0
6
45
78
0
0
6
0
% P
% Gln:
0
0
6
0
6
6
0
0
6
0
0
0
0
0
0
% Q
% Arg:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% R
% Ser:
0
6
0
0
0
0
0
0
0
6
6
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
6
0
0
84
0
6
% T
% Val:
0
0
0
6
84
6
0
0
0
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
78
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _