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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC1
All Species:
50.3
Human Site:
T373
Identified Species:
65.1
UniProt:
P62191
Number Species:
17
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62191
NP_002793.2
440
49185
T373
Q
I
H
T
S
R
M
T
L
A
D
D
V
T
L
Chimpanzee
Pan troglodytes
XP_001142567
399
44420
R333
K
V
I
M
A
T
N
R
I
E
T
L
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001103312
440
49180
T373
Q
I
H
T
S
R
M
T
L
A
D
D
V
T
L
Dog
Lupus familis
XP_848524
440
49333
T373
Q
I
H
T
S
R
M
T
L
A
D
A
V
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
I344
D
R
R
Q
K
R
L
I
F
S
T
I
T
S
K
Rat
Rattus norvegicus
P62193
440
49166
T373
Q
I
H
T
S
R
M
T
L
A
D
D
V
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517805
388
43713
L322
I
H
T
S
R
M
T
L
A
D
D
V
T
L
D
Chicken
Gallus gallus
Q90732
440
49185
T373
Q
I
H
T
S
R
M
T
L
A
D
D
V
T
L
Frog
Xenopus laevis
P46470
461
52229
E390
K
V
M
Q
K
D
S
E
K
N
M
S
I
K
K
Zebra Danio
Brachydanio rerio
NP_001002091
440
49193
T373
Q
I
H
T
S
R
M
T
V
A
E
D
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
T372
T
I
H
T
S
R
M
T
L
A
E
D
V
N
L
Honey Bee
Apis mellifera
XP_623527
440
49215
T373
S
I
H
T
S
R
M
T
L
A
P
D
V
N
L
Nematode Worm
Caenorhab. elegans
O16368
443
49704
T376
Q
I
H
T
S
R
M
T
L
G
K
E
V
N
L
Sea Urchin
Strong. purpuratus
XP_796230
443
49683
T376
N
I
H
T
S
R
M
T
L
S
N
D
V
N
L
Poplar Tree
Populus trichocarpa
XP_002301829
446
49676
T379
Q
I
H
T
A
R
M
T
L
A
D
D
V
N
L
Maize
Zea mays
NP_001146268
446
49429
T379
Q
I
H
T
S
K
M
T
L
A
D
D
V
N
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL67
443
49328
T376
Q
I
H
T
S
K
M
T
L
A
E
D
V
N
L
Baker's Yeast
Sacchar. cerevisiae
P40327
437
48810
N370
G
I
H
T
S
K
M
N
L
S
E
D
V
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
99.7
97
N.A.
45
100
N.A.
88.1
98.6
42.2
97.2
N.A.
91.3
91.8
83
89.6
Protein Similarity:
100
90.4
100
98.1
N.A.
68.1
100
N.A.
88.1
99
60
99.5
N.A.
95.9
96.3
92.7
95.2
P-Site Identity:
100
0
100
93.3
N.A.
6.6
100
N.A.
6.6
100
0
80
N.A.
80
80
73.3
73.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
26.6
100
N.A.
13.3
100
20
100
N.A.
86.6
80
80
86.6
Percent
Protein Identity:
77.3
76
N.A.
77.4
71.3
N.A.
Protein Similarity:
90.5
90.3
N.A.
90.5
85.6
N.A.
P-Site Identity:
86.6
86.6
N.A.
80
60
N.A.
P-Site Similarity:
93.3
93.3
N.A.
93.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
6
62
0
6
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
6
0
0
0
6
45
67
6
0
6
% D
% Glu:
0
0
0
0
0
0
0
6
0
6
23
6
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% F
% Gly:
6
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% G
% His:
0
6
78
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
78
6
0
0
0
0
6
6
0
0
6
6
0
0
% I
% Lys:
12
0
0
0
12
17
0
0
6
0
6
0
0
6
12
% K
% Leu:
0
0
0
0
0
0
6
6
73
0
0
6
0
6
78
% L
% Met:
0
0
6
6
0
6
78
0
0
0
6
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
6
6
0
6
6
0
0
45
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
6
0
0
6
0
% P
% Gln:
56
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
6
6
0
6
67
0
6
0
0
0
0
0
0
0
% R
% Ser:
6
0
0
6
73
0
6
0
0
17
0
6
0
12
0
% S
% Thr:
6
0
6
78
0
6
6
73
0
0
12
0
12
28
0
% T
% Val:
0
12
0
0
0
0
0
0
6
0
0
6
78
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _