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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMC1
All Species:
49.09
Human Site:
S126
Identified Species:
63.53
UniProt:
P62191
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62191
NP_002793.2
440
49185
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Chimpanzee
Pan troglodytes
XP_001142567
399
44420
R103
R
S
K
V
D
D
L
R
G
T
P
M
S
V
G
Rhesus Macaque
Macaca mulatta
XP_001103312
440
49180
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
I
Dog
Lupus familis
XP_848524
440
49333
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
P54775
418
47263
Y111
A
S
T
T
G
S
N
Y
Y
V
R
M
V
S
T
Rat
Rattus norvegicus
P62193
440
49166
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517805
388
43713
P94
V
D
K
D
L
L
E
P
G
C
S
V
L
L
N
Chicken
Gallus gallus
Q90732
440
49185
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Frog
Xenopus laevis
P46470
461
52229
H119
R
N
D
S
Y
T
L
H
K
I
L
P
N
K
V
Zebra Danio
Brachydanio rerio
NP_001002091
440
49193
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48601
439
49305
S125
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Honey Bee
Apis mellifera
XP_623527
440
49215
S126
N
H
A
I
V
S
T
S
V
G
S
E
H
Y
V
Nematode Worm
Caenorhab. elegans
O16368
443
49704
N129
Q
H
A
I
V
S
T
N
V
G
S
E
H
Y
V
Sea Urchin
Strong. purpuratus
XP_796230
443
49683
S129
N
H
A
I
V
S
A
S
V
G
S
E
Y
Y
V
Poplar Tree
Populus trichocarpa
XP_002301829
446
49676
S132
N
H
A
I
V
S
S
S
V
G
P
E
Y
Y
V
Maize
Zea mays
NP_001146268
446
49429
S132
S
H
A
I
V
S
S
S
V
G
P
E
Y
Y
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL67
443
49328
S129
N
H
A
I
V
S
S
S
V
G
P
E
Y
Y
V
Baker's Yeast
Sacchar. cerevisiae
P40327
437
48810
P123
D
H
A
I
V
T
S
P
T
M
P
D
Y
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
99.7
97
N.A.
45
100
N.A.
88.1
98.6
42.2
97.2
N.A.
91.3
91.8
83
89.6
Protein Similarity:
100
90.4
100
98.1
N.A.
68.1
100
N.A.
88.1
99
60
99.5
N.A.
95.9
96.3
92.7
95.2
P-Site Identity:
100
0
93.3
100
N.A.
6.6
100
N.A.
6.6
100
6.6
100
N.A.
100
100
86.6
86.6
P-Site Similarity:
100
6.6
100
100
N.A.
6.6
100
N.A.
13.3
100
26.6
100
N.A.
100
100
93.3
93.3
Percent
Protein Identity:
77.3
76
N.A.
77.4
71.3
N.A.
Protein Similarity:
90.5
90.3
N.A.
90.5
85.6
N.A.
P-Site Identity:
80
73.3
N.A.
80
40
N.A.
P-Site Similarity:
93.3
93.3
N.A.
93.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
78
0
0
0
6
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
6
6
6
6
6
6
0
0
0
0
0
6
0
0
0
% D
% Glu:
0
0
0
0
0
0
6
0
0
0
0
73
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
6
0
0
0
12
73
0
0
0
0
6
% G
% His:
0
78
0
0
0
0
0
6
0
0
0
0
50
0
0
% H
% Ile:
0
0
0
78
0
0
0
0
0
6
0
0
0
0
6
% I
% Lys:
0
0
12
0
0
0
0
0
6
0
0
0
0
6
0
% K
% Leu:
0
0
0
0
6
6
12
0
0
0
6
0
6
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
12
0
0
0
% M
% Asn:
62
6
0
0
0
0
6
6
0
0
0
0
6
0
6
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
28
6
0
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
6
0
0
6
0
0
0
0
% R
% Ser:
6
12
0
6
0
78
23
67
0
0
62
0
6
6
0
% S
% Thr:
0
0
6
6
0
12
50
0
6
6
0
0
0
0
6
% T
% Val:
6
0
0
6
78
0
0
0
73
6
0
6
6
6
78
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
6
6
0
0
0
28
78
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _