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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP46
All Species:
38.48
Human Site:
Y54
Identified Species:
56.44
UniProt:
P62068
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62068
NP_001127695.1
366
42442
Y54
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
Y361
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
Y163
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Dog
Lupus familis
XP_849650
389
45094
Y77
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
Y58
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Rat
Rattus norvegicus
XP_214034
366
42397
Y54
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515746
420
47812
Y108
S
P
V
L
R
A
L
Y
F
C
R
P
F
R
E
Chicken
Gallus gallus
O57429
357
40913
R54
C
L
Q
N
Q
Y
L
R
D
L
N
N
N
S
R
Frog
Xenopus laevis
Q52KZ6
370
42846
Y58
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Zebra Danio
Brachydanio rerio
A5WWB0
370
42886
Y54
N
S
V
L
Q
A
L
Y
F
C
R
P
F
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732801
364
41625
Y55
F
R
E
K
V
L
E
Y
K
A
K
N
K
R
P
Honey Bee
Apis mellifera
XP_625039
354
40655
Y55
F
R
E
K
V
L
E
Y
K
A
R
N
K
R
T
Nematode Worm
Caenorhab. elegans
P34547
426
48259
N57
P
F
R
E
K
V
L
N
Y
K
Q
T
L
K
K
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
A59
P
F
R
D
R
V
L
A
Y
K
T
A
P
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
E64
N
N
K
A
D
A
E
E
N
L
L
T
C
L
A
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
S367
S
P
E
H
R
K
K
S
A
L
I
R
G
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.5
68
91.2
N.A.
87.3
99.7
N.A.
80.9
24.8
87.5
94.3
N.A.
72.6
74.3
60
77
Protein Similarity:
100
51.2
72.4
91.7
N.A.
92.4
100
N.A.
83.5
44.2
92.4
95.9
N.A.
82.5
83.6
72
86.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
13.3
100
100
N.A.
13.3
20
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
13.3
100
100
N.A.
20
20
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
59.2
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.6
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
63
0
7
7
13
0
7
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
57
0
0
7
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
19
7
0
0
19
7
0
0
0
0
0
0
57
% E
% Phe:
13
13
0
0
0
0
0
0
57
0
0
0
57
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
7
13
7
7
7
0
13
13
7
0
13
13
13
% K
% Leu:
0
7
0
57
0
13
75
0
0
19
7
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
57
7
0
7
0
0
0
7
7
0
7
19
7
0
0
% N
% Pro:
13
13
0
0
0
0
0
0
0
0
0
57
7
7
7
% P
% Gln:
0
0
7
0
57
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
13
13
0
19
0
0
7
0
0
63
7
0
69
7
% R
% Ser:
13
50
0
0
0
0
0
7
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
13
0
0
7
% T
% Val:
0
0
57
0
13
13
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
69
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _