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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP46
All Species:
52.42
Human Site:
Y272
Identified Species:
76.89
UniProt:
P62068
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62068
NP_001127695.1
366
42442
Y272
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
Y579
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
Y381
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Dog
Lupus familis
XP_849650
389
45094
Y295
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
Y276
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Rat
Rattus norvegicus
XP_214034
366
42397
Y272
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515746
420
47812
Y326
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Chicken
Gallus gallus
O57429
357
40913
T269
I
R
A
S
K
L
T
T
F
V
N
F
P
L
K
Frog
Xenopus laevis
Q52KZ6
370
42846
Y276
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Zebra Danio
Brachydanio rerio
A5WWB0
370
42886
Y276
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732801
364
41625
H268
N
R
H
I
K
V
S
H
R
V
V
F
P
L
E
Honey Bee
Apis mellifera
XP_625039
354
40655
H258
N
R
H
I
K
V
S
H
R
V
V
F
P
L
E
Nematode Worm
Caenorhab. elegans
P34547
426
48259
Y301
N
R
H
T
K
L
S
Y
R
V
V
F
P
L
E
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
Y270
H
R
Y
T
K
L
S
Y
R
V
V
F
P
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
Y271
G
R
Y
K
K
L
S
Y
R
V
V
F
P
L
E
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
N580
N
C
N
I
K
L
F
N
N
I
H
Y
P
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.5
68
91.2
N.A.
87.3
99.7
N.A.
80.9
24.8
87.5
94.3
N.A.
72.6
74.3
60
77
Protein Similarity:
100
51.2
72.4
91.7
N.A.
92.4
100
N.A.
83.5
44.2
92.4
95.9
N.A.
82.5
83.6
72
86.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
46.6
100
100
N.A.
66.6
66.6
86.6
100
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
66.6
100
100
N.A.
93.3
93.3
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
59.2
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.6
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
86.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
88
% E
% Phe:
0
0
0
0
0
0
7
0
7
0
0
94
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
63
0
19
0
0
0
0
13
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
19
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
7
100
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
88
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
0
7
0
0
0
0
7
7
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
94
0
0
0
0
0
0
88
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
88
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
69
0
0
7
7
0
0
0
0
0
0
7
% T
% Val:
0
0
0
0
0
13
0
0
0
94
88
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
69
0
0
0
0
75
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _