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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP46
All Species:
46.36
Human Site:
S286
Identified Species:
68
UniProt:
P62068
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62068
NP_001127695.1
366
42442
S286
E
L
R
L
F
N
T
S
S
D
A
V
N
L
D
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
S593
E
L
R
L
F
N
T
S
G
D
A
T
N
P
D
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
S395
E
L
R
L
F
N
T
S
G
D
A
T
N
P
D
Dog
Lupus familis
XP_849650
389
45094
S309
E
L
R
L
F
N
T
S
S
D
A
V
N
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
S290
E
L
R
L
F
N
T
S
G
D
A
T
N
P
D
Rat
Rattus norvegicus
XP_214034
366
42397
S286
E
L
R
L
F
N
T
S
S
D
A
V
N
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515746
420
47812
S340
E
L
R
L
F
N
T
S
S
D
A
V
N
L
D
Chicken
Gallus gallus
O57429
357
40913
F283
K
D
L
D
L
R
E
F
A
S
Q
S
C
N
H
Frog
Xenopus laevis
Q52KZ6
370
42846
S290
E
L
R
L
F
N
T
S
G
D
A
T
N
P
D
Zebra Danio
Brachydanio rerio
A5WWB0
370
42886
S290
E
L
R
L
F
N
T
S
G
D
A
V
N
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732801
364
41625
S282
E
L
R
L
F
N
T
S
D
D
A
V
N
P
D
Honey Bee
Apis mellifera
XP_625039
354
40655
S272
E
L
R
L
F
N
T
S
D
D
A
V
N
P
D
Nematode Worm
Caenorhab. elegans
P34547
426
48259
S315
E
L
R
L
F
N
V
S
D
D
A
E
Y
G
D
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
S284
E
L
R
L
M
N
T
S
D
D
A
E
A
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
V285
E
L
K
L
S
N
T
V
D
E
Y
V
D
I
E
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
I594
T
L
N
V
C
S
S
I
N
S
K
V
C
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.5
68
91.2
N.A.
87.3
99.7
N.A.
80.9
24.8
87.5
94.3
N.A.
72.6
74.3
60
77
Protein Similarity:
100
51.2
72.4
91.7
N.A.
92.4
100
N.A.
83.5
44.2
92.4
95.9
N.A.
82.5
83.6
72
86.6
P-Site Identity:
100
80
80
100
N.A.
80
100
N.A.
100
0
80
93.3
N.A.
86.6
86.6
66.6
66.6
P-Site Similarity:
100
80
80
100
N.A.
80
100
N.A.
100
13.3
80
93.3
N.A.
86.6
86.6
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
59.2
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.6
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
82
0
7
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
0
7
0
7
0
0
0
0
32
82
0
0
7
0
82
% D
% Glu:
88
0
0
0
0
0
7
0
0
7
0
13
0
0
7
% E
% Phe:
0
0
0
0
75
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
32
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% I
% Lys:
7
0
7
0
0
0
0
0
0
0
7
0
0
0
7
% K
% Leu:
0
94
7
88
7
0
0
0
0
0
0
0
0
32
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
88
0
0
7
0
0
0
69
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
44
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% Q
% Arg:
0
0
82
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
7
7
7
82
25
13
0
7
0
0
0
% S
% Thr:
7
0
0
0
0
0
82
0
0
0
0
25
0
0
0
% T
% Val:
0
0
0
7
0
0
7
7
0
0
0
57
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _