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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP46
All Species:
51.82
Human Site:
S199
Identified Species:
76
UniProt:
P62068
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P62068
NP_001127695.1
366
42442
S199
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Chimpanzee
Pan troglodytes
XP_001135418
673
75605
S506
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Rhesus Macaque
Macaca mulatta
XP_001117796
475
54263
S308
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Dog
Lupus familis
XP_849650
389
45094
S222
D
E
D
F
L
A
L
S
V
D
V
E
Q
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9M2
370
42895
S203
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Rat
Rattus norvegicus
XP_214034
366
42397
S199
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515746
420
47812
S253
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Chicken
Gallus gallus
O57429
357
40913
S194
F
D
P
F
W
D
L
S
L
P
I
P
K
K
G
Frog
Xenopus laevis
Q52KZ6
370
42846
S203
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Zebra Danio
Brachydanio rerio
A5WWB0
370
42886
S203
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732801
364
41625
Q195
D
E
N
F
F
D
L
Q
V
D
V
D
Q
N
T
Honey Bee
Apis mellifera
XP_625039
354
40655
Q185
D
E
D
F
F
D
L
Q
V
D
V
D
Q
N
T
Nematode Worm
Caenorhab. elegans
P34547
426
48259
S228
D
E
D
F
L
D
L
S
I
D
V
E
Q
N
T
Sea Urchin
Strong. purpuratus
XP_783431
365
41716
S197
D
E
D
F
L
D
L
S
V
D
V
E
Q
N
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LAM0
365
41828
S198
D
E
T
F
L
D
L
S
L
D
I
E
Q
N
S
Baker's Yeast
Sacchar. cerevisiae
P38187
747
83846
P505
D
E
P
F
L
D
F
P
I
E
V
Q
G
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.5
68
91.2
N.A.
87.3
99.7
N.A.
80.9
24.8
87.5
94.3
N.A.
72.6
74.3
60
77
Protein Similarity:
100
51.2
72.4
91.7
N.A.
92.4
100
N.A.
83.5
44.2
92.4
95.9
N.A.
82.5
83.6
72
86.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
100
26.6
100
100
N.A.
73.3
80
93.3
100
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
53.3
100
100
N.A.
86.6
86.6
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
59.2
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.6
33.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
94
7
75
0
0
94
0
0
0
88
0
13
0
7
0
% D
% Glu:
0
94
0
0
0
0
0
0
0
7
0
75
0
0
7
% E
% Phe:
7
0
0
100
13
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% K
% Leu:
0
0
0
0
82
0
94
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
88
0
% N
% Pro:
0
0
13
0
0
0
0
7
0
7
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
0
7
88
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
7
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
82
% T
% Val:
0
0
0
0
0
0
0
0
75
0
88
0
0
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _