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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSME3
All Species:
19.09
Human Site:
S24
Identified Species:
42
UniProt:
P61289
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61289
NP_005780.2
254
29506
S24
S
F
R
E
R
I
T
S
E
A
E
D
L
V
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537633
268
30969
S24
S
F
R
E
R
I
T
S
E
A
E
D
L
V
A
Cat
Felis silvestris
Mouse
Mus musculus
P97371
249
28654
K24
F
R
E
D
L
C
S
K
T
E
N
L
L
G
S
Rat
Rattus norvegicus
Q63797
249
28558
K24
F
R
E
D
L
C
S
K
T
E
N
L
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3J5
254
29463
S24
S
F
R
E
R
I
T
S
E
A
E
D
L
V
A
Frog
Xenopus laevis
NP_001088027
254
29435
S24
C
F
R
E
R
I
T
S
E
A
E
D
L
V
A
Zebra Danio
Brachydanio rerio
NP_571451
256
29295
S24
A
F
R
E
R
I
T
S
E
A
E
D
L
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572866
245
28103
T25
L
K
A
E
L
L
I
T
K
G
F
P
E
N
I
Honey Bee
Apis mellifera
XP_393883
245
27989
L25
T
K
A
E
Q
L
L
L
K
G
F
P
E
K
I
Nematode Worm
Caenorhab. elegans
NP_499493
248
28670
A24
K
Q
K
L
F
A
E
A
E
R
L
V
K
E
E
Sea Urchin
Strong. purpuratus
XP_790819
249
28217
V24
H
Q
M
S
E
N
L
V
K
V
L
F
P
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
94.7
N.A.
40.9
41.3
N.A.
N.A.
96.4
91.3
80
N.A.
47.6
51.1
49.2
50
Protein Similarity:
100
N.A.
N.A.
94.7
N.A.
64.9
65.3
N.A.
N.A.
97.6
95.6
90.6
N.A.
71.2
74.8
72
73.2
P-Site Identity:
100
N.A.
N.A.
100
N.A.
6.6
6.6
N.A.
N.A.
100
93.3
93.3
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
26.6
26.6
N.A.
N.A.
100
93.3
100
N.A.
26.6
33.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
0
10
0
10
0
46
0
0
0
0
46
% A
% Cys:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
0
0
0
0
0
46
0
0
0
% D
% Glu:
0
0
19
64
10
0
10
0
55
19
46
0
19
10
10
% E
% Phe:
19
46
0
0
10
0
0
0
0
0
19
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
19
0
0
0
19
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
46
10
0
0
0
0
0
0
0
19
% I
% Lys:
10
19
10
0
0
0
0
19
28
0
0
0
10
10
10
% K
% Leu:
10
0
0
10
28
19
19
10
0
0
19
19
64
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
19
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
19
10
0
0
% P
% Gln:
0
19
0
0
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
19
46
0
46
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
28
0
0
10
0
0
19
46
0
0
0
0
0
0
19
% S
% Thr:
10
0
0
0
0
0
46
10
19
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
10
0
10
0
46
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _