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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAP2B All Species: 44.85
Human Site: S146 Identified Species: 70.48
UniProt: P61225 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61225 NP_002877.2 183 20504 S146 S C P F M E T S A K N K A S V
Chimpanzee Pan troglodytes XP_001140638 589 63249 S552 S C P F M E T S A K N K A S V
Rhesus Macaque Macaca mulatta XP_001088490 184 20704 S147 G C P F M E T S A K S K T M V
Dog Lupus familis XP_534168 335 38190 S298 G C P F M E T S A K S K T M V
Cat Felis silvestris
Mouse Mus musculus Q8BU31 183 20726 S146 G C P F M E T S A K S K S M V
Rat Rattus norvegicus P61227 183 20486 S146 S C P F M E T S A K N K A S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514804 244 27079 S146 G C P F M E T S A K S K T M V
Chicken Gallus gallus XP_001233104 403 43650 S366 G C P F M E T S A K S K T M V
Frog Xenopus laevis Q7ZXH7 184 20815 S147 N C A F L E S S A K S K I N V
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 S147 S C A F L E S S A K S K I N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845 S146 N C A F M E T S A K A K V N V
Honey Bee Apis mellifera XP_001120003 181 20317 F142 A Q L W G C P F V E A S A K H
Nematode Worm Caenorhab. elegans NP_506707 181 20375 C140 A L A E S W S C P F T E C S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 S147 R V P F Y E T S A L L R S N V
Red Bread Mold Neurospora crassa Q01387 229 25331 S170 G C E F T E A S A K T R T N V
Conservation
Percent
Protein Identity: 100 31 89.1 47.7 N.A. 85.7 100 N.A. 67.2 40.6 61.4 61.9 N.A. 60.8 70.4 68.3 N.A.
Protein Similarity: 100 31 93.4 51.3 N.A. 92.9 100 N.A. 71.3 42.9 77.1 77.1 N.A. 77.7 83.6 80.8 N.A.
P-Site Identity: 100 100 73.3 73.3 N.A. 73.3 100 N.A. 73.3 73.3 53.3 60 N.A. 66.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 80 80 N.A. 86.6 100 N.A. 80 80 86.6 86.6 N.A. 80 26.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.2 40.6
Protein Similarity: N.A. N.A. N.A. N.A. 52.2 56.7
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 27 0 0 0 7 0 87 0 14 0 27 0 7 % A
% Cys: 0 80 0 0 0 7 0 7 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 7 0 87 0 0 0 7 0 7 0 0 0 % E
% Phe: 0 0 0 87 0 0 0 7 0 7 0 0 0 0 0 % F
% Gly: 40 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 80 0 74 0 7 0 % K
% Leu: 0 7 7 0 14 0 0 0 0 7 7 0 0 0 0 % L
% Met: 0 0 0 0 60 0 0 0 0 0 0 0 0 34 0 % M
% Asn: 14 0 0 0 0 0 0 0 0 0 20 0 0 34 0 % N
% Pro: 0 0 60 0 0 0 7 0 7 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 14 0 0 0 % R
% Ser: 27 0 0 0 7 0 20 87 0 0 47 7 14 27 0 % S
% Thr: 0 0 0 0 7 0 67 0 0 0 14 0 34 0 0 % T
% Val: 0 7 0 0 0 0 0 0 7 0 0 0 7 0 87 % V
% Trp: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _