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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCE1
All Species:
43.8
Human Site:
Y594
Identified Species:
68.83
UniProt:
P61221
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61221
NP_001035809.1
599
67314
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Chimpanzee
Pan troglodytes
XP_001147081
599
67141
G594
R
K
V
V
L
N
H
G
L
L
I
S
V
_
_
Rhesus Macaque
Macaca mulatta
XP_001095891
596
66830
V590
I
K
V
C
R
K
I
V
L
N
H
G
S
L
_
Dog
Lupus familis
XP_532679
599
67310
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001101916
599
67282
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514246
599
67394
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Chicken
Gallus gallus
NP_001006440
599
67337
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Frog
Xenopus laevis
NP_001080761
599
67517
Y594
D
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Zebra Danio
Brachydanio rerio
NP_998718
599
67269
Y594
E
Q
K
K
S
G
N
Y
F
F
L
D
D
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648272
611
69280
F602
E
Q
K
R
S
G
Q
F
F
F
L
E
D
E
A
Honey Bee
Apis mellifera
XP_623630
608
68415
Y603
E
Q
K
K
A
G
Q
Y
F
F
L
E
E
_
_
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203141
586
66508
F581
E
Q
K
R
N
G
N
F
F
F
L
E
D
_
_
Poplar Tree
Populus trichocarpa
XP_002328845
603
68059
Y598
E
Q
K
A
A
G
S
Y
Y
Y
L
D
D
_
_
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LPJ4
605
68371
Y600
E
Q
K
S
A
G
S
Y
Y
Y
L
D
D
_
_
Baker's Yeast
Sacchar. cerevisiae
Q03195
608
68322
Y600
E
Q
K
S
S
G
N
Y
F
F
L
D
N
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
98.1
99.8
N.A.
N.A.
99.8
N.A.
99.1
98.8
93.3
90.3
N.A.
75.7
79.7
N.A.
77.3
Protein Similarity:
100
98
98.5
100
N.A.
N.A.
100
N.A.
100
99.5
97.5
95.6
N.A.
86.4
88.9
N.A.
86.8
P-Site Identity:
100
0
0
100
N.A.
N.A.
100
N.A.
100
100
92.3
100
N.A.
60
69.2
N.A.
69.2
P-Site Similarity:
100
23
7.1
100
N.A.
N.A.
100
N.A.
100
100
100
100
N.A.
80
92.3
N.A.
100
Percent
Protein Identity:
75.9
N.A.
N.A.
75.3
68
N.A.
Protein Similarity:
86.5
N.A.
N.A.
85.9
82.7
N.A.
P-Site Identity:
61.5
N.A.
N.A.
61.5
73.3
N.A.
P-Site Similarity:
92.3
N.A.
N.A.
92.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
20
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
67
74
0
0
% D
% Glu:
80
0
0
0
0
0
0
0
0
0
0
20
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
14
74
74
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
87
0
7
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
0
14
87
54
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
0
0
14
7
87
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
7
60
0
0
7
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
87
0
0
0
0
14
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
14
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
14
60
0
14
0
0
0
0
7
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
14
7
0
0
0
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
14
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
87
% _