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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCE1
All Species:
49.39
Human Site:
S423
Identified Species:
77.62
UniProt:
P61221
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61221
NP_001035809.1
599
67314
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Chimpanzee
Pan troglodytes
XP_001147081
599
67141
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Rhesus Macaque
Macaca mulatta
XP_001095891
596
66830
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Dog
Lupus familis
XP_532679
599
67310
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001101916
599
67282
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514246
599
67394
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Chicken
Gallus gallus
NP_001006440
599
67337
S423
I
S
P
K
S
T
G
S
V
R
Q
L
L
H
E
Frog
Xenopus laevis
NP_001080761
599
67517
S423
I
S
P
K
A
S
G
S
V
R
Q
L
L
H
E
Zebra Danio
Brachydanio rerio
NP_998718
599
67269
S423
I
S
P
K
F
K
G
S
V
R
A
L
L
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648272
611
69280
H431
I
S
P
K
F
Q
N
H
V
R
H
L
L
H
D
Honey Bee
Apis mellifera
XP_623630
608
68415
I432
I
S
P
K
S
Q
G
I
V
R
Q
L
L
H
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203141
586
66508
T410
I
S
P
K
S
Q
G
T
V
R
Q
L
L
H
A
Poplar Tree
Populus trichocarpa
XP_002328845
603
68059
S427
I
S
P
K
F
Q
F
S
V
R
Q
L
L
H
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LPJ4
605
68371
S429
I
S
P
K
F
Q
N
S
V
R
H
L
L
H
Q
Baker's Yeast
Sacchar. cerevisiae
Q03195
608
68322
T429
I
A
P
K
F
P
G
T
V
R
Q
L
F
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
98.1
99.8
N.A.
N.A.
99.8
N.A.
99.1
98.8
93.3
90.3
N.A.
75.7
79.7
N.A.
77.3
Protein Similarity:
100
98
98.5
100
N.A.
N.A.
100
N.A.
100
99.5
97.5
95.6
N.A.
86.4
88.9
N.A.
86.8
P-Site Identity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
86.6
73.3
N.A.
60
86.6
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
N.A.
100
N.A.
100
100
100
80
N.A.
66.6
86.6
N.A.
86.6
Percent
Protein Identity:
75.9
N.A.
N.A.
75.3
68
N.A.
Protein Similarity:
86.5
N.A.
N.A.
85.9
82.7
N.A.
P-Site Identity:
73.3
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
0
0
0
0
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% E
% Phe:
0
0
0
0
34
0
7
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
0
0
0
0
80
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
14
0
0
94
0
% H
% Ile:
100
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
100
0
7
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
100
94
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
100
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
34
0
0
0
0
80
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% R
% Ser:
0
94
0
0
60
7
0
74
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
47
0
14
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _