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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2F
All Species:
52.42
Human Site:
Y115
Identified Species:
82.38
UniProt:
P61218
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61218
NP_068809.1
127
14478
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Chimpanzee
Pan troglodytes
XP_001163169
126
14136
A113
T
V
L
R
P
S
Y
A
L
A
H
G
L
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531740
127
14402
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
O88828
127
14446
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514439
127
14491
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Chicken
Gallus gallus
NP_990065
127
14462
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Frog
Xenopus laevis
NP_001088632
127
14406
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Zebra Danio
Brachydanio rerio
NP_001002544
127
14553
Y115
R
Y
L
P
D
G
S
Y
E
D
W
G
C
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24320
131
14704
Y118
R
Y
L
P
D
H
S
Y
E
D
W
S
I
D
E
Honey Bee
Apis mellifera
XP_393973
130
14813
Y117
R
Y
L
P
D
N
S
Y
E
D
W
G
I
D
E
Nematode Worm
Caenorhab. elegans
Q17684
137
15965
Y124
R
Y
L
P
D
G
S
Y
E
D
W
P
T
D
Q
Sea Urchin
Strong. purpuratus
XP_787961
124
14068
Y113
R
Y
L
P
D
G
S
Y
E
D
W
G
C
D
E
Poplar Tree
Populus trichocarpa
XP_002322450
143
16470
Y122
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Maize
Zea mays
NP_001149930
142
16402
Y121
R
Y
L
P
D
G
S
Y
E
D
W
G
V
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20435
155
17891
F143
R
Y
L
P
D
G
S
F
E
D
W
S
V
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.3
N.A.
99.2
N.A.
N.A.
99.2
N.A.
99.2
97.6
93.6
87.4
N.A.
63.3
71.5
57.6
70
Protein Similarity:
100
84.2
N.A.
99.2
N.A.
N.A.
100
N.A.
99.2
97.6
96
92.1
N.A.
74
83
71.5
78.7
P-Site Identity:
100
13.3
N.A.
100
N.A.
N.A.
100
N.A.
100
100
100
93.3
N.A.
80
86.6
80
93.3
P-Site Similarity:
100
20
N.A.
100
N.A.
N.A.
100
N.A.
100
100
100
93.3
N.A.
86.6
93.3
86.6
93.3
Percent
Protein Identity:
55.9
55.6
N.A.
N.A.
50.9
N.A.
Protein Similarity:
69.2
70.4
N.A.
N.A.
64.5
N.A.
P-Site Identity:
100
100
N.A.
N.A.
80
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% C
% Asp:
0
0
0
0
94
0
0
0
0
94
0
0
0
87
0
% D
% Glu:
0
0
0
0
0
0
0
0
94
0
0
0
0
7
87
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
80
0
0
0
0
0
80
0
7
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
7
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
94
7
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
94
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
94
0
0
0
0
14
0
0
7
% S
% Thr:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
0
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
94
0
0
0
0
% W
% Tyr:
0
94
0
0
0
0
7
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _