KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1A
All Species:
21.82
Human Site:
T248
Identified Species:
30
UniProt:
P61163
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61163
NP_005727.1
376
42614
T248
Y
Y
L
P
D
G
S
T
I
E
I
G
P
S
R
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
T248
Y
T
L
P
D
G
S
T
L
D
V
G
P
A
R
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
T248
Y
T
L
P
D
G
S
T
L
D
V
G
P
A
R
Dog
Lupus familis
XP_854473
376
42271
V248
Y
T
L
P
D
G
S
V
L
D
V
G
P
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
T248
Y
T
L
P
D
G
S
T
L
D
V
G
P
A
R
Rat
Rattus norvegicus
P68035
377
42000
P245
L
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
A221
V
K
T
I
K
E
R
A
C
Y
L
S
I
N
P
Chicken
Gallus gallus
P08023
377
41976
P245
L
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
Frog
Xenopus laevis
P10995
377
41970
P245
L
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
T248
Y
T
L
P
D
G
S
T
L
D
I
G
P
A
R
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
P245
L
E
K
S
Y
E
L
P
D
G
Q
V
I
T
I
Fruit Fly
Dros. melanogaster
P45889
376
42701
I248
Y
K
L
P
D
G
K
I
F
E
I
G
P
A
R
Honey Bee
Apis mellifera
XP_623834
376
42650
Y248
Y
I
L
P
D
G
S
Y
L
E
I
G
P
A
R
Nematode Worm
Caenorhab. elegans
NP_497108
374
42053
I247
A
L
P
D
T
T
K
I
E
I
S
N
S
L
F
Sea Urchin
Strong. purpuratus
XP_796462
375
42304
H247
Y
T
L
P
D
G
S
H
L
E
V
G
Q
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
P245
V
E
K
N
Y
E
L
P
D
G
Q
V
I
T
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
Y246
D
P
A
K
I
A
E
Y
V
L
P
D
G
N
K
Conservation
Percent
Protein Identity:
100
90.1
90.9
90.9
N.A.
91.2
53.3
N.A.
91.4
53
53
93
53.3
79.2
84.5
69.9
88.3
Protein Similarity:
100
97.6
97.6
97.6
N.A.
97.6
74.2
N.A.
91.4
74.2
74.2
98.1
74.2
92
94.1
84.8
94.9
P-Site Identity:
100
66.6
66.6
60
N.A.
66.6
0
N.A.
0
0
0
73.3
0
66.6
73.3
0
53.3
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
93.3
6.6
N.A.
13.3
6.6
6.6
93.3
6.6
73.3
86.6
0
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.1
N.A.
63.1
Protein Similarity:
N.A.
N.A.
N.A.
75.8
N.A.
81
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
0
6
0
6
0
0
0
0
0
48
0
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
6
0
0
6
53
0
0
0
30
30
0
6
0
0
0
% D
% Glu:
0
30
0
0
0
36
6
0
6
24
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
53
0
0
0
30
0
53
6
0
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
6
6
0
0
12
6
6
24
0
36
0
30
% I
% Lys:
0
12
30
6
6
0
12
0
0
0
0
0
0
0
12
% K
% Leu:
24
6
53
0
0
0
30
0
42
6
6
0
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
0
0
0
0
0
0
6
0
12
0
% N
% Pro:
0
6
6
53
0
0
0
30
0
0
6
0
48
0
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
30
0
6
0
0
% Q
% Arg:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
48
% R
% Ser:
0
0
0
24
0
0
48
0
0
0
6
6
6
6
0
% S
% Thr:
0
36
6
0
6
6
0
30
0
0
0
0
0
30
0
% T
% Val:
12
0
0
0
0
0
0
6
6
0
30
30
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
53
6
0
0
30
0
0
12
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _