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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR1A All Species: 58.48
Human Site: S339 Identified Species: 80.42
UniProt: P61163 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P61163 NP_005727.1 376 42614 S339 A P Q E R L Y S T W I G G S I
Chimpanzee Pan troglodytes XP_001155293 376 42274 S339 A P Q E R L Y S T W I G G S I
Rhesus Macaque Macaca mulatta XP_001101028 376 42275 S339 A P Q E R L Y S T W I G G S I
Dog Lupus familis XP_854473 376 42271 S339 A P Q E R L Y S T W I G G S I
Cat Felis silvestris
Mouse Mus musculus Q8R5C5 376 42263 S339 A P Q E R L Y S T W I G G S I
Rat Rattus norvegicus P68035 377 42000 S340 A P P E R K Y S V W I G G S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509975 345 38928 G309 G G S T L F K G F G D R L L S
Chicken Gallus gallus P08023 377 41976 S340 A P P E R K Y S V W I G G S I
Frog Xenopus laevis P10995 377 41970 S340 A P P E R K Y S V W I G G S I
Zebra Danio Brachydanio rerio NP_998537 376 42387 S339 A P Q E R L Y S T W I G G S I
Tiger Blowfish Takifugu rubipres P53480 377 41956 S340 A P P E R K Y S V W I G G S I
Fruit Fly Dros. melanogaster P45889 376 42701 S339 A P Q E R L Y S T W M G G S I
Honey Bee Apis mellifera XP_623834 376 42650 S339 A P Q E R L Y S T W I G G S I
Nematode Worm Caenorhab. elegans NP_497108 374 42053 L337 A S Q E R N S L T W I G G S I
Sea Urchin Strong. purpuratus XP_796462 375 42304 S338 A P Q E R L Y S T W I G G S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P53492 377 41717 S340 A P P E R K Y S V W I G G S I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P38673 380 42364 S344 A P P E R K Y S T W I G G S I
Conservation
Percent
Protein Identity: 100 90.1 90.9 90.9 N.A. 91.2 53.3 N.A. 91.4 53 53 93 53.3 79.2 84.5 69.9 88.3
Protein Similarity: 100 97.6 97.6 97.6 N.A. 97.6 74.2 N.A. 91.4 74.2 74.2 98.1 74.2 92 94.1 84.8 94.9
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. 0 80 80 100 80 93.3 100 73.3 100
P-Site Similarity: 100 100 100 100 N.A. 100 80 N.A. 0 80 80 100 80 100 100 73.3 100
Percent
Protein Identity: N.A. N.A. N.A. 54.1 N.A. 63.1
Protein Similarity: N.A. N.A. N.A. 75.8 N.A. 81
P-Site Identity: N.A. N.A. N.A. 80 N.A. 86.6
P-Site Similarity: N.A. N.A. N.A. 80 N.A. 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 95 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % D
% Glu: 0 0 0 95 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 6 0 0 6 0 0 0 0 0 0 % F
% Gly: 6 6 0 0 0 0 0 6 0 6 0 95 95 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 89 0 0 0 95 % I
% Lys: 0 0 0 0 0 36 6 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 6 53 0 6 0 0 0 0 6 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 89 36 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 95 0 0 0 0 0 0 6 0 0 0 % R
% Ser: 0 6 6 0 0 0 6 89 0 0 0 0 0 95 6 % S
% Thr: 0 0 0 6 0 0 0 0 65 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 95 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _