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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1A
All Species:
40.61
Human Site:
S316
Identified Species:
55.83
UniProt:
P61163
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61163
NP_005727.1
376
42614
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Dog
Lupus familis
XP_854473
376
42271
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Rat
Rattus norvegicus
P68035
377
42000
K317
G
I
A
D
R
M
Q
K
E
I
T
A
L
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
S286
L
V
F
A
I
Q
K
S
D
M
D
L
R
R
T
Chicken
Gallus gallus
P08023
377
41976
K317
G
I
A
D
R
M
Q
K
E
I
T
A
L
A
P
Frog
Xenopus laevis
P10995
377
41970
K317
G
I
A
D
R
M
Q
K
E
I
T
A
L
A
P
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
K317
G
I
A
D
R
M
Q
K
E
I
T
A
L
A
P
Fruit Fly
Dros. melanogaster
P45889
376
42701
S316
G
F
G
D
R
L
L
S
E
L
K
K
H
S
A
Honey Bee
Apis mellifera
XP_623834
376
42650
S316
G
F
G
D
R
L
L
S
E
I
R
K
M
A
P
Nematode Worm
Caenorhab. elegans
NP_497108
374
42053
G314
G
F
G
D
R
L
L
G
E
M
R
K
I
A
P
Sea Urchin
Strong. purpuratus
XP_796462
375
42304
S315
G
F
G
D
R
L
L
S
E
V
K
N
L
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
K317
G
I
A
D
R
M
S
K
E
I
T
A
L
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
T321
G
F
G
D
R
L
L
T
E
V
Q
K
L
A
V
Conservation
Percent
Protein Identity:
100
90.1
90.9
90.9
N.A.
91.2
53.3
N.A.
91.4
53
53
93
53.3
79.2
84.5
69.9
88.3
Protein Similarity:
100
97.6
97.6
97.6
N.A.
97.6
74.2
N.A.
91.4
74.2
74.2
98.1
74.2
92
94.1
84.8
94.9
P-Site Identity:
100
100
100
100
N.A.
100
46.6
N.A.
6.6
46.6
46.6
100
46.6
73.3
80
73.3
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
20
60
60
100
60
86.6
100
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.1
N.A.
63.1
Protein Similarity:
N.A.
N.A.
N.A.
75.8
N.A.
81
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
80
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
6
0
0
0
0
0
0
0
30
0
89
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
95
0
0
0
0
6
0
6
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
95
0
0
0
0
0
0
% E
% Phe:
0
65
6
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
95
0
65
0
0
0
0
6
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
30
0
0
6
0
0
0
0
36
0
0
6
0
0
% I
% Lys:
0
0
0
0
0
0
6
30
0
0
48
59
0
0
0
% K
% Leu:
6
0
0
0
0
65
65
0
0
6
0
6
77
0
0
% L
% Met:
0
0
0
0
0
30
0
0
0
12
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
83
% P
% Gln:
0
0
0
0
0
6
24
0
0
0
6
0
0
0
0
% Q
% Arg:
0
0
0
0
95
0
0
0
0
0
12
0
6
6
0
% R
% Ser:
0
0
0
0
0
0
6
59
0
0
0
0
0
6
0
% S
% Thr:
0
0
0
0
0
0
0
6
0
0
30
0
0
0
6
% T
% Val:
0
6
0
0
0
0
0
0
0
48
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _