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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1A
All Species:
37.88
Human Site:
S272
Identified Species:
52.08
UniProt:
P61163
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61163
NP_005727.1
376
42614
S272
P
D
L
I
G
E
E
S
E
G
I
H
E
V
L
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
L
Dog
Lupus familis
XP_854473
376
42271
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
L
Rat
Rattus norvegicus
P68035
377
42000
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
Y242
E
T
E
K
A
Q
Y
Y
L
P
D
G
S
T
I
Chicken
Gallus gallus
P08023
377
41976
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
T
Frog
Xenopus laevis
P10995
377
41970
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
A
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
S272
P
D
L
I
G
D
E
S
E
G
I
H
E
V
L
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
S273
P
S
F
I
G
M
E
S
A
G
I
H
E
T
A
Fruit Fly
Dros. melanogaster
P45889
376
42701
C272
P
D
L
L
G
E
E
C
E
G
I
H
D
V
L
Honey Bee
Apis mellifera
XP_623834
376
42650
C272
P
D
L
I
G
E
E
C
E
G
L
H
E
V
L
Nematode Worm
Caenorhab. elegans
NP_497108
374
42053
W270
P
D
L
I
G
T
E
W
P
G
M
A
H
V
V
Sea Urchin
Strong. purpuratus
XP_796462
375
42304
C271
P
D
L
I
G
E
E
C
E
G
L
H
E
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
A273
P
S
L
I
G
M
E
A
P
G
I
H
E
T
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
Y277
P
E
I
I
G
L
E
Y
P
G
V
H
Q
I
V
Conservation
Percent
Protein Identity:
100
90.1
90.9
90.9
N.A.
91.2
53.3
N.A.
91.4
53
53
93
53.3
79.2
84.5
69.9
88.3
Protein Similarity:
100
97.6
97.6
97.6
N.A.
97.6
74.2
N.A.
91.4
74.2
74.2
98.1
74.2
92
94.1
84.8
94.9
P-Site Identity:
100
73.3
80
80
N.A.
80
60
N.A.
0
60
60
93.3
60
80
86.6
53.3
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
13.3
60
60
100
60
93.3
93.3
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.1
N.A.
63.1
Protein Similarity:
N.A.
N.A.
N.A.
75.8
N.A.
81
P-Site Identity:
N.A.
N.A.
N.A.
60
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
0
0
6
24
0
0
6
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
18
0
0
0
0
0
0
0
% C
% Asp:
0
59
0
0
0
30
0
0
0
0
6
0
6
0
0
% D
% Glu:
6
6
6
0
0
24
95
0
53
0
0
0
77
0
0
% E
% Phe:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
95
0
0
0
0
95
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
89
6
0
0
% H
% Ile:
0
0
6
65
0
0
0
0
0
0
48
0
0
6
6
% I
% Lys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
65
6
0
6
0
0
6
0
36
0
0
0
48
% L
% Met:
0
0
0
0
0
30
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
95
0
0
0
0
0
0
0
18
6
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
0
6
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
30
0
0
0
0
0
59
0
0
0
0
6
0
0
% S
% Thr:
0
6
0
0
0
6
0
0
0
0
0
0
0
36
18
% T
% Val:
0
0
0
24
0
0
0
0
0
0
6
0
0
59
18
% V
% Trp:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _