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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR1A
All Species:
27.27
Human Site:
S225
Identified Species:
37.5
UniProt:
P61163
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61163
NP_005727.1
376
42614
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Chimpanzee
Pan troglodytes
XP_001155293
376
42274
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Rhesus Macaque
Macaca mulatta
XP_001101028
376
42275
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Dog
Lupus familis
XP_854473
376
42271
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5C5
376
42263
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Rat
Rattus norvegicus
P68035
377
42000
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509975
345
38928
L198
S
R
F
L
R
L
Y
L
R
K
E
G
Y
D
F
Chicken
Gallus gallus
P08023
377
41976
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Frog
Xenopus laevis
P10995
377
41970
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Zebra Danio
Brachydanio rerio
NP_998537
376
42387
S225
K
E
R
A
C
Y
L
S
L
N
P
Q
K
D
E
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
A222
K
E
K
L
C
Y
V
A
L
D
F
E
N
E
M
Fruit Fly
Dros. melanogaster
P45889
376
42701
A225
K
E
K
V
C
Y
L
A
T
N
P
Q
K
E
E
Honey Bee
Apis mellifera
XP_623834
376
42650
A225
K
E
R
A
C
Y
L
A
S
N
P
Q
K
E
E
Nematode Worm
Caenorhab. elegans
NP_497108
374
42053
A224
K
E
N
A
C
Y
L
A
L
D
P
T
K
V
E
Sea Urchin
Strong. purpuratus
XP_796462
375
42304
S224
K
E
Q
S
C
Y
L
S
I
N
P
Q
K
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P53492
377
41717
A222
K
E
K
L
A
Y
V
A
L
D
Y
E
Q
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P38673
380
42364
A223
K
E
S
V
T
Y
V
A
H
D
P
R
K
E
E
Conservation
Percent
Protein Identity:
100
90.1
90.9
90.9
N.A.
91.2
53.3
N.A.
91.4
53
53
93
53.3
79.2
84.5
69.9
88.3
Protein Similarity:
100
97.6
97.6
97.6
N.A.
97.6
74.2
N.A.
91.4
74.2
74.2
98.1
74.2
92
94.1
84.8
94.9
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
6.6
26.6
26.6
93.3
26.6
66.6
80
60
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
6.6
73.3
73.3
100
73.3
86.6
93.3
80
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.1
N.A.
63.1
Protein Similarity:
N.A.
N.A.
N.A.
75.8
N.A.
81
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
48
6
0
0
53
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
83
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
42
0
0
0
48
0
% D
% Glu:
0
95
0
0
0
0
0
0
0
0
6
30
0
48
65
% E
% Phe:
0
0
6
0
0
0
0
0
0
0
24
0
0
0
6
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
36
0
0
0
0
0
0
% I
% Lys:
95
0
36
0
0
0
0
0
0
6
0
0
65
0
0
% K
% Leu:
0
0
0
36
0
6
59
6
42
0
0
0
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% M
% Asn:
0
0
6
0
0
0
0
0
0
53
0
0
24
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
65
0
0
0
0
% P
% Gln:
0
0
6
0
0
0
0
0
0
0
0
53
6
0
0
% Q
% Arg:
0
6
42
0
6
0
0
0
6
0
0
6
0
0
0
% R
% Ser:
6
0
6
6
0
0
0
42
6
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
6
0
0
0
6
0
0
6
0
0
0
% T
% Val:
0
0
0
12
0
0
36
0
0
0
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
95
6
0
0
0
6
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _