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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42
All Species:
52.12
Human Site:
T138
Identified Species:
76.44
UniProt:
P60953
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60953
NP_001034891.1
191
21311
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Chimpanzee
Pan troglodytes
XP_001159920
191
21268
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Rhesus Macaque
Macaca mulatta
XP_001117007
191
21241
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Dog
Lupus familis
XP_849332
191
21210
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P60766
191
21292
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Rat
Rattus norvegicus
Q6RUV5
192
21432
T138
E
K
K
L
T
P
I
T
Y
P
Q
G
L
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516353
201
22485
T154
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
Chicken
Gallus gallus
Q90694
191
21254
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Frog
Xenopus laevis
NP_001079368
191
21285
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Zebra Danio
Brachydanio rerio
NP_001018130
191
21351
T138
K
N
K
Q
K
P
I
T
P
E
T
A
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40793
191
21384
T138
K
N
K
Q
K
P
I
T
M
E
Q
G
E
K
L
Honey Bee
Apis mellifera
XP_394608
191
21185
S138
K
N
K
Q
K
P
I
S
A
E
Q
G
E
K
L
Nematode Worm
Caenorhab. elegans
Q05062
191
21147
S138
K
N
K
Q
K
P
V
S
T
D
V
G
E
K
L
Sea Urchin
Strong. purpuratus
XP_789429
191
21304
T138
K
N
K
Q
K
P
T
T
G
E
A
G
E
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38912
198
21710
A141
G
A
V
P
I
S
T
A
Q
G
E
E
L
K
K
Baker's Yeast
Sacchar. cerevisiae
P19073
191
21304
T138
R
Q
R
L
R
P
I
T
S
E
Q
G
S
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
94.2
94.7
N.A.
100
70.3
N.A.
84
95.2
96.3
99.4
N.A.
91.6
91
86.3
88.4
Protein Similarity:
100
96.8
96.8
96.8
N.A.
100
81.2
N.A.
84.5
97.3
97.9
99.4
N.A.
94.2
95.2
94.7
94.2
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
26.6
100
100
100
N.A.
80
73.3
60
60
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
33.3
100
100
100
N.A.
80
80
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54
79.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
87.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
7
7
0
7
50
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
7
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
82
7
7
75
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
7
7
0
38
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
75
0
7
0
0
0
0
0
0
% I
% Lys:
75
7
82
0
75
0
0
0
0
0
7
0
0
82
7
% K
% Leu:
0
7
0
13
0
0
0
0
0
0
0
7
13
0
75
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
13
% M
% Asn:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
7
0
94
0
0
50
7
0
0
0
0
0
% P
% Gln:
0
7
0
75
0
0
0
0
7
0
25
0
0
0
0
% Q
% Arg:
7
0
13
0
7
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
0
7
7
13
7
0
0
0
7
0
0
% S
% Thr:
0
0
0
0
7
0
13
82
7
0
50
0
0
0
0
% T
% Val:
0
0
7
0
0
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _