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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAS2R46 All Species: 8.18
Human Site: S216 Identified Species: 45
UniProt: P59540 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P59540 NP_795368.2 309 35523 S216 M Q L H G K G S Q D P S M K V
Chimpanzee Pan troglodytes Q646C0 309 35573 S216 M Q L H G K G S Q D P S M K V
Rhesus Macaque Macaca mulatta Q645T3 308 35334 S216 M Q L R D K G S Q D P S T K V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q7M721 295 33576 K203 L L I Y S L S K H L K N M K F
Rat Rattus norvegicus Q675B7 330 37340 P238 M R L Y G K G P H N P S A S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 85.4 N.A. N.A. 48.2 42.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98 90.6 N.A. N.A. 66.9 63 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 80 N.A. N.A. 13.3 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 80 N.A. N.A. 40 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 20 0 0 0 0 60 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % F
% Gly: 0 0 0 0 60 0 80 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 40 0 0 0 0 40 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 80 0 20 0 0 20 0 0 80 0 % K
% Leu: 20 20 80 0 0 20 0 0 0 20 0 0 0 0 0 % L
% Met: 80 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 20 0 20 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 20 0 0 80 0 0 0 0 % P
% Gln: 0 60 0 0 0 0 0 0 60 0 0 0 0 0 0 % Q
% Arg: 0 20 0 20 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 20 0 20 60 0 0 0 80 0 20 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _