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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC26A5
All Species:
16.67
Human Site:
S623
Identified Species:
33.33
UniProt:
P58743
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58743
NP_945350.1
744
81264
S623
Y
P
P
I
V
I
K
S
T
F
P
E
E
M
Q
Chimpanzee
Pan troglodytes
XP_001145955
504
54853
L387
L
C
N
S
I
G
S
L
F
Q
T
F
S
I
S
Rhesus Macaque
Macaca mulatta
XP_001084716
505
55044
Q389
N
S
I
G
S
L
F
Q
T
F
S
I
S
C
S
Dog
Lupus familis
XP_540393
744
81203
S623
Y
P
P
I
V
I
K
S
T
F
P
E
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99NH7
744
81302
T623
F
P
P
I
V
I
K
T
T
F
P
E
E
L
Q
Rat
Rattus norvegicus
Q9EPH0
744
81260
T623
F
P
P
I
V
I
K
T
T
F
P
E
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507963
744
81520
P622
S
G
K
G
P
A
E
P
I
V
Q
N
T
F
P
Chicken
Gallus gallus
NP_001072945
742
81094
N626
A
N
D
G
L
P
A
N
G
K
F
A
F
V
D
Frog
Xenopus laevis
NP_001086349
726
79928
T594
A
K
N
I
L
S
K
T
Q
M
G
T
G
L
E
Zebra Danio
Brachydanio rerio
NP_958881
739
81386
K623
L
N
G
P
Q
K
P
K
H
V
H
T
N
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94225
782
87457
T647
V
D
Y
L
G
L
S
T
L
K
S
V
Y
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FY46
685
75077
R568
N
R
G
L
E
V
D
R
I
N
F
V
I
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.6
67.6
96.7
N.A.
94.8
94.4
N.A.
77.6
58.7
43.1
52.8
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
100
67.7
67.7
98.3
N.A.
97.5
97.4
N.A.
87.5
75.8
60.6
69.8
N.A.
N.A.
N.A.
47.5
N.A.
P-Site Identity:
100
0
13.3
93.3
N.A.
80
80
N.A.
0
0
13.3
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
20
100
N.A.
100
100
N.A.
6.6
20
40
6.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
9
0
9
0
0
0
0
34
34
0
17
% E
% Phe:
17
0
0
0
0
0
9
0
9
42
17
9
9
9
0
% F
% Gly:
0
9
17
25
9
9
0
0
9
0
9
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
9
42
9
34
0
0
17
0
0
9
9
9
0
% I
% Lys:
0
9
9
0
0
9
42
9
0
17
0
0
0
0
0
% K
% Leu:
17
0
0
17
17
17
0
9
9
0
0
0
0
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% M
% Asn:
17
17
17
0
0
0
0
9
0
9
0
9
9
0
0
% N
% Pro:
0
34
34
9
9
9
9
9
0
0
34
0
0
0
9
% P
% Gln:
0
0
0
0
9
0
0
9
9
9
9
0
0
0
42
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
9
9
9
17
17
0
0
17
0
17
0
17
% S
% Thr:
0
0
0
0
0
0
0
34
42
0
9
17
9
0
0
% T
% Val:
9
0
0
0
34
9
0
0
0
17
0
17
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _