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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC26A5
All Species:
30.61
Human Site:
S549
Identified Species:
61.21
UniProt:
P58743
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58743
NP_945350.1
744
81264
S549
A
P
I
Y
Y
A
N
S
D
L
Y
S
N
A
L
Chimpanzee
Pan troglodytes
XP_001145955
504
54853
D316
L
K
E
S
Y
N
V
D
V
V
G
T
L
P
L
Rhesus Macaque
Macaca mulatta
XP_001084716
505
55044
V318
E
S
Y
N
V
D
V
V
G
T
L
P
L
G
L
Dog
Lupus familis
XP_540393
744
81203
S549
A
P
I
Y
Y
A
N
S
D
L
Y
S
N
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99NH7
744
81302
S549
A
P
I
Y
Y
A
N
S
D
L
Y
S
S
A
L
Rat
Rattus norvegicus
Q9EPH0
744
81260
S549
A
P
I
Y
Y
A
N
S
D
L
Y
S
S
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507963
744
81520
S548
A
P
I
Y
Y
A
N
S
D
L
Y
N
N
A
L
Chicken
Gallus gallus
NP_001072945
742
81094
S555
T
S
L
Y
F
A
N
S
E
S
Y
T
S
A
L
Frog
Xenopus laevis
NP_001086349
726
79928
S521
E
T
D
L
Y
R
D
S
E
E
N
S
M
A
K
Zebra Danio
Brachydanio rerio
NP_958881
739
81386
S552
S
S
I
Y
F
A
N
S
E
L
Y
V
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94225
782
87457
S570
A
P
L
I
F
T
S
S
D
R
F
T
M
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FY46
685
75077
A497
A
F
V
I
H
E
S
A
N
P
H
I
A
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.6
67.6
96.7
N.A.
94.8
94.4
N.A.
77.6
58.7
43.1
52.8
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
100
67.7
67.7
98.3
N.A.
97.5
97.4
N.A.
87.5
75.8
60.6
69.8
N.A.
N.A.
N.A.
47.5
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
93.3
93.3
N.A.
93.3
46.6
26.6
60
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
26.6
6.6
100
N.A.
100
100
N.A.
100
80
40
80
N.A.
N.A.
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
59
0
9
0
0
0
0
9
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
9
9
50
0
0
0
0
0
0
% D
% Glu:
17
0
9
0
0
9
0
0
25
9
0
0
0
0
0
% E
% Phe:
0
9
0
0
25
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
9
0
0
9
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
50
17
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% K
% Leu:
9
0
17
9
0
0
0
0
0
50
9
0
17
0
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
9
0
9
59
0
9
0
9
9
25
0
0
% N
% Pro:
0
50
0
0
0
0
0
0
0
9
0
9
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% R
% Ser:
9
25
0
9
0
0
17
75
0
9
0
42
25
9
0
% S
% Thr:
9
9
0
0
0
9
0
0
0
9
0
25
0
0
0
% T
% Val:
0
0
9
0
9
0
17
9
9
9
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
59
59
0
0
0
0
0
59
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _