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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SESN2
All Species:
16.06
Human Site:
S285
Identified Species:
32.12
UniProt:
P58004
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58004
NP_113647.1
480
54494
S285
T
S
Q
E
E
M
E
S
R
F
E
L
E
K
S
Chimpanzee
Pan troglodytes
XP_524552
488
55721
S293
T
S
Q
E
E
M
E
S
R
F
E
L
E
K
S
Rhesus Macaque
Macaca mulatta
XP_001113030
480
54574
S285
T
S
Q
E
E
M
E
S
R
F
E
L
E
K
S
Dog
Lupus familis
XP_544461
485
54499
S290
A
S
Q
E
E
M
E
S
R
F
E
L
E
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P58043
480
54358
N285
A
S
Q
E
E
M
E
N
R
F
E
L
E
K
S
Rat
Rattus norvegicus
NP_001102828
480
54455
N285
A
S
Q
E
E
M
E
N
R
F
E
L
E
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521763
476
54883
M281
E
E
A
S
Q
E
E
M
A
S
R
F
E
I
E
Chicken
Gallus gallus
XP_419796
546
62460
M351
E
E
A
S
Q
E
E
M
A
T
R
F
E
R
E
Frog
Xenopus laevis
P58003
481
55440
E286
E
E
E
A
S
Q
E
E
M
A
T
R
F
E
R
Zebra Danio
Brachydanio rerio
NP_001002660
488
56574
M293
E
E
A
S
Q
E
E
M
A
T
R
F
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K5
497
55835
S302
C
S
E
A
E
L
S
S
R
F
Q
K
V
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4D6
474
55090
Y283
P
P
C
N
Y
P
I
Y
S
H
H
R
T
F
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
98.9
94
N.A.
91.4
91.8
N.A.
57
52.7
55.2
55.7
N.A.
30.7
N.A.
21.8
N.A.
Protein Similarity:
100
94
99.5
96.6
N.A.
95
95.4
N.A.
70.6
65.1
69.4
68.6
N.A.
47.2
N.A.
39.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
13.3
13.3
6.6
13.3
N.A.
33.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
26.6
20
26.6
N.A.
60
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
25
17
0
0
0
0
25
9
0
0
0
0
0
% A
% Cys:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
34
34
17
50
59
25
84
9
0
0
50
0
75
17
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
59
0
25
9
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
0
50
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
50
0
0
0
% L
% Met:
0
0
0
0
0
50
0
25
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
9
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
25
9
0
0
0
0
9
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
59
0
25
17
0
17
9
% R
% Ser:
0
59
0
25
9
0
9
42
9
9
0
0
0
0
42
% S
% Thr:
25
0
0
0
0
0
0
0
0
17
9
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _