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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SESN2
All Species:
10.91
Human Site:
S254
Identified Species:
21.82
UniProt:
P58004
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58004
NP_113647.1
480
54494
S254
N
N
S
G
G
F
E
S
A
R
D
V
E
A
L
Chimpanzee
Pan troglodytes
XP_524552
488
55721
S262
N
N
S
G
G
F
E
S
A
R
D
V
E
A
L
Rhesus Macaque
Macaca mulatta
XP_001113030
480
54574
S254
N
N
S
G
G
F
E
S
A
R
E
V
E
A
L
Dog
Lupus familis
XP_544461
485
54499
A259
N
N
S
G
G
F
E
A
A
R
D
V
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P58043
480
54358
A254
N
N
S
G
G
F
E
A
A
R
D
V
E
A
L
Rat
Rattus norvegicus
NP_001102828
480
54455
A254
N
N
S
G
G
F
E
A
A
R
D
I
E
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521763
476
54883
A250
S
P
A
G
T
V
P
A
T
D
S
W
C
E
V
Chicken
Gallus gallus
XP_419796
546
62460
S317
I
H
A
S
P
A
A
S
I
P
T
T
E
S
V
Frog
Xenopus laevis
P58003
481
55440
V251
G
T
E
G
H
L
P
V
G
I
V
M
P
T
D
Zebra Danio
Brachydanio rerio
NP_001002660
488
56574
N259
A
Q
E
D
M
F
G
N
Q
Q
V
S
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K5
497
55835
P271
L
A
T
A
Q
Q
L
P
Q
Q
H
G
I
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4D6
474
55090
N254
T
Y
S
S
N
R
K
N
Y
S
P
V
L
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
98.9
94
N.A.
91.4
91.8
N.A.
57
52.7
55.2
55.7
N.A.
30.7
N.A.
21.8
N.A.
Protein Similarity:
100
94
99.5
96.6
N.A.
95
95.4
N.A.
70.6
65.1
69.4
68.6
N.A.
47.2
N.A.
39.5
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
6.6
13.3
6.6
13.3
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
40
13.3
33.3
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
9
0
9
9
34
50
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
9
42
0
0
0
9
% D
% Glu:
0
0
17
0
0
0
50
0
0
0
9
0
67
9
0
% E
% Phe:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
67
50
0
9
0
9
0
0
9
0
0
0
% G
% His:
0
9
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
9
9
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
9
9
0
0
0
0
0
9
9
59
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
50
50
0
0
9
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
9
0
17
9
0
9
9
0
9
0
0
% P
% Gln:
0
9
0
0
9
9
0
0
17
17
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
50
0
0
0
0
0
% R
% Ser:
9
0
59
17
0
0
0
34
0
9
9
9
0
25
9
% S
% Thr:
9
9
9
0
9
0
0
0
9
0
9
9
0
9
0
% T
% Val:
0
0
0
0
0
9
0
9
0
0
17
50
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _