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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
33.33
Human Site:
Y371
Identified Species:
52.38
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
Y371
T
F
D
N
V
T
S
Y
L
K
K
K
E
E
R
Chimpanzee
Pan troglodytes
XP_514923
412
45566
Y371
T
F
D
N
M
T
S
Y
L
K
K
K
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
Y370
T
F
D
N
M
T
S
Y
L
K
K
K
E
E
R
Dog
Lupus familis
XP_544908
406
45137
Y371
T
F
D
N
V
T
A
Y
L
R
K
K
E
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
Y373
T
F
D
N
M
T
S
Y
L
K
K
K
E
E
R
Rat
Rattus norvegicus
NP_001129139
365
40341
A333
W
Q
A
A
P
D
D
A
V
S
Q
R
L
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
Y455
T
F
D
N
M
A
T
Y
L
K
R
K
E
E
R
Chicken
Gallus gallus
XP_416749
417
46882
Y381
S
F
D
N
M
A
V
Y
L
Q
K
K
E
E
R
Frog
Xenopus laevis
Q7ZY78
396
43627
T364
A
V
F
D
N
M
A
T
Y
L
Q
K
K
E
L
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
Y373
N
F
D
N
M
A
S
Y
L
Q
K
K
Q
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
N381
V
L
D
G
L
G
A
N
E
E
G
A
P
P
F
Honey Bee
Apis mellifera
XP_001120270
256
29743
S224
V
Y
I
I
N
N
T
S
N
I
Q
Q
N
L
F
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
R356
N
Q
Q
E
Y
E
K
R
K
A
D
K
F
E
Q
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
N402
P
I
E
G
A
T
G
N
G
D
A
A
K
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
I410
S
N
E
F
D
S
A
I
I
Q
S
V
Q
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
93.3
93.3
86.6
N.A.
93.3
0
N.A.
73.3
66.6
13.3
66.6
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
93.3
86.6
40
86.6
N.A.
26.6
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
7
20
27
7
0
7
7
14
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
60
7
7
7
7
0
0
7
7
0
0
0
7
% D
% Glu:
0
0
14
7
0
7
0
0
7
7
0
0
47
67
0
% E
% Phe:
0
54
7
7
0
0
0
0
0
0
0
0
7
0
14
% F
% Gly:
0
0
0
14
0
7
7
0
7
0
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
7
0
0
0
7
7
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
7
34
47
67
14
0
0
% K
% Leu:
0
7
0
0
7
0
0
0
54
7
0
0
7
7
7
% L
% Met:
0
0
0
0
40
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
7
0
54
14
7
0
14
7
0
0
0
7
0
0
% N
% Pro:
7
0
0
0
7
0
0
0
0
0
0
0
7
7
0
% P
% Gln:
0
14
7
0
0
0
0
0
0
20
20
7
14
0
7
% Q
% Arg:
0
0
0
0
0
0
0
7
0
7
7
7
0
7
54
% R
% Ser:
14
0
0
0
0
7
34
7
0
7
7
0
0
0
7
% S
% Thr:
40
0
0
0
0
40
14
7
0
0
0
0
0
0
7
% T
% Val:
14
7
0
0
14
0
7
0
7
0
0
7
0
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
7
0
0
54
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _