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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR4
All Species:
28.79
Human Site:
Y361
Identified Species:
45.24
UniProt:
P57081
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57081
NP_061139.2
412
45490
Y361
D
A
S
F
S
S
L
Y
K
A
T
F
D
N
V
Chimpanzee
Pan troglodytes
XP_514923
412
45566
Y361
D
A
S
F
S
S
L
Y
K
A
T
F
D
N
M
Rhesus Macaque
Macaca mulatta
XP_001105050
411
45737
Y360
D
A
N
F
S
S
L
Y
K
A
T
F
D
N
M
Dog
Lupus familis
XP_544908
406
45137
Y361
D
V
G
F
S
G
L
Y
K
A
T
F
D
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP82
413
45737
Y363
D
D
S
F
R
S
L
Y
K
A
T
F
D
N
M
Rat
Rattus norvegicus
NP_001129139
365
40341
G323
L
A
L
W
R
P
M
G
S
E
W
Q
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511691
493
54884
Y445
E
G
G
F
K
N
L
Y
K
A
T
F
D
N
M
Chicken
Gallus gallus
XP_416749
417
46882
Y371
E
S
H
Y
S
S
L
Y
K
A
S
F
D
N
M
Frog
Xenopus laevis
Q7ZY78
396
43627
L354
P
E
S
R
F
V
G
L
Y
K
A
V
F
D
N
Zebra Danio
Brachydanio rerio
A4IGH4
413
46222
Y363
E
S
Q
F
K
H
L
Y
K
V
N
F
D
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W415
424
46480
L371
S
G
V
P
E
G
W
L
K
M
V
L
D
G
L
Honey Bee
Apis mellifera
XP_001120270
256
29743
L214
I
S
F
Y
N
N
S
L
L
L
V
Y
I
I
N
Nematode Worm
Caenorhab. elegans
Q23232
388
43620
T346
D
N
L
F
K
N
V
T
H
N
N
Q
Q
E
Y
Sea Urchin
Strong. purpuratus
XP_001202437
434
48995
K392
A
R
R
W
N
K
S
K
K
R
P
I
E
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03774
444
50470
N400
E
N
S
F
V
V
N
N
E
K
S
N
E
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
91.5
79.1
N.A.
75.3
64.8
N.A.
56.1
56.3
48.2
44.3
N.A.
27.8
24.7
25.7
32.4
Protein Similarity:
100
99.2
94.4
86.4
N.A.
83.2
74
N.A.
67.5
72.4
63.5
61
N.A.
44
38.1
42.2
52.7
P-Site Identity:
100
93.3
86.6
80
N.A.
80
6.6
N.A.
60
60
6.6
46.6
N.A.
13.3
0
13.3
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
20
N.A.
80
93.3
13.3
66.6
N.A.
20
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
27
0
0
0
0
0
0
0
47
7
0
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
7
0
0
0
0
0
0
0
0
0
0
60
7
7
% D
% Glu:
27
7
0
0
7
0
0
0
7
7
0
0
14
7
0
% E
% Phe:
0
0
7
60
7
0
0
0
0
0
0
54
7
7
0
% F
% Gly:
0
14
14
0
0
14
7
7
0
0
0
0
0
14
0
% G
% His:
0
0
7
0
0
7
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% I
% Lys:
0
0
0
0
20
7
0
7
67
14
0
0
0
0
0
% K
% Leu:
7
0
14
0
0
0
54
20
7
7
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
40
% M
% Asn:
0
14
7
0
14
20
7
7
0
7
14
7
0
54
14
% N
% Pro:
7
0
0
7
0
7
0
0
0
0
7
0
0
0
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
14
7
0
0
% Q
% Arg:
0
7
7
7
14
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
20
34
0
34
34
14
0
7
0
14
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
40
0
0
0
0
% T
% Val:
0
7
7
0
7
14
7
0
0
7
14
7
0
0
14
% V
% Trp:
0
0
0
14
0
0
7
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
14
0
0
0
54
7
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _